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VIDEO: Vitamin C may kill cancer cells in KRAS–mutant colorectal cancer

NEW ORLEANS — Lewis Cantley, PhD, director of the Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine and NewYork-Presbyterian, describes how KRAS-mutant colorectal cancers appear susceptible to vitamin C.

The doses of vitamin C necessary to induce cell death are far higher than those in traditional diets or supplements, so IV administration would be required.

“We’re now beginning to design trials to test this in human patients with KRAS–mutant colorectal cancers, as a consortium with other institutions,” Cantley said.

NEW ORLEANS — Lewis Cantley, PhD, director of the Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine and NewYork-Presbyterian, describes how KRAS-mutant colorectal cancers appear susceptible to vitamin C.

The doses of vitamin C necessary to induce cell death are far higher than those in traditional diets or supplements, so IV administration would be required.

“We’re now beginning to design trials to test this in human patients with KRAS–mutant colorectal cancers, as a consortium with other institutions,” Cantley said.

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