CAR T-cell therapy has some patients crowdfunding to cover costs

September 13, 2019
Aletta Weiss plans to undergo chimeric antigen receptor T-cell treatment for relapsed large B-cell lymphoma, and she’s turning to GoFundMe for…

Meeting News

Speaker: Rationale exists to test CAR T-cell therapy in KRAS-mutated lung cancer

September 11, 2019
BARCELONA — Enriched cell surface expression of mesothelin in

FDA News

T-cell therapy receives FDA’s orphan drug status for soft tissue sarcoma

September 9, 2019
The FDA has granted orphan drug designation to ADP-A2M4, an investigational specific peptide-enhanced affinity receptor T-cell therapy, for the…

FDA News

FDA grants orphan drug status to anti-BCMA CAR T-cell therapy for multiple myeloma

September 5, 2019
The FDA has given orphan drug status to CT053, an investigational chimeric antigen receptor T-cell therapy for the treatment of multiple myeloma. …

Trend Watch

Celgene, Immatics strike deal on adoptive cell therapy development

August 29, 2019
Immatics Biotechnologies, a Germany-based biopharma company, has entered into a strategic agreement with Celgene on the development of new adoptive…

FDA News

FDA provides pathway to BLA approval for chronic heart failure cell therapy

August 28, 2019
The FDA has established a pathway to marketing for Revascor, an investigational cell therapy used for the prevention of postimplantation mucosal…

FDA News

FDA grants fast track designation to cell therapy for degenerative disk disease

August 27, 2019
The FDA has given its fast track designation to the investigational cell therapy IDCT for the treatment of degenerative disc disease. IDCT…

$9 million grant funds trial of CAR T-cell therapy for metastatic breast cancer

August 25, 2019
California Institute for Regenerative Medicine awarded a $9.28 million grant will support a clinical trial at City of Hope to evaluate chimeric…

Trend Watch

Stanford, Johns Hopkins cancer researchers share Albany Prize

August 23, 2019
Two researchers will share the 2019 Albany Medical Center Prize in Medicine and Biomedical Research.

In the Journals

Dual CAR T-cell combination a ‘promising treatment option’ for multiple myeloma

August 20, 2019
A combination of humanized anti-CD19 and anti-B-cell maturation antigen chimeric antigen receptor T-cells has shown activity in patients with…


‘Smarter and stronger’ T cells offer hope for more effective, less toxic cancer therapy

August 18, 2019
Editor’s note: This is the first in a series of articles that spotlight research efforts supported through Cancer Research Institute’s…

Trend Watch

SITC elects three new board members

August 16, 2019
The Society for Immunotherapy of Cancer has elected three new members to its board of directors who will begin their three-year terms in January…

Trend Watch

Phio, Helmholtz Zentrum München partner to develop cell therapies for solid tumors

August 15, 2019
Biotech firm Phio Pharmaceuticals announced it has entered into a research collaboration with Helmholtz Zentrum München, the German Research…

In the JournalsPerspective

CAR T-cell therapy shows activity in lymphoma despite lack of measurable disease

August 14, 2019
Tisagenlecleucel showed measurable in vivo expansion in patients with relapsed or refractory diffuse large B-cell lymphoma who had no measurable…


Patient access to new cancer treatments — an uncertain and fragile process

HemOnc Today, August 10, 2019
John Sweetenham, MD
As Tom Brokaw eloquently stated, uncertainty is at the heart of the cancer experience for our patients. It impacts many aspects of their lives, from…

Trend Watch

CAR T-cell therapy made available to all Medicare recipients

August 8, 2019
On Wednesday, the Trump Administration made chimeric antigen receptor T-cell therapy available to all Medicare beneficiaries via a long-awaited final…

Trend Watch

CMS increases CAR T reimbursement by 15%

August 5, 2019
CMS has finalized its plan to increase its new technology add-on payment to 65% of the total cost of chimeric antigen T-cell therapies. The payment…

In the Journals

Stem cell therapy safe, feasible in congenital heart defect surgery

July 29, 2019
Intramyocardial injection of autologous umbilical cord blood-derived mononuclear cells into the right ventricular myocardium has shown to be both…

In the Journals

Highly activated natural killer cells safe, efficient for advanced lung cancer

July 26, 2019
More than 80% of patients with advanced lung cancer achieved stable disease after receiving investigational therapy of highly activated natural…

FDA News

Mustang Bio’s CAR T-cell therapy receives orphan drug designation for AML

July 25, 2019
The FDA has granted orphan drug designation to MB-102, an investigational chimeric antigen receptor T-cell therapy for patients with acute myeloid…