SAN FRANCISCO — Despite established consensus, guidelines and treatment protocols, researchers observed racial and ethnic disparities in clinical presentation, treatment and outcomes, according to study findings.
The researchers examined the National Inpatient Sample to examine racial/ethnic disparities by stage of disease and comorbidities, postoperative complications and mortality, and surgical treatment allocation (breast-conserving surgery vs. mastectomy). The National Inpatient Sample, which includes data compiled from 44 states, represents 95% of all hospital discharges in the United States.
The researchers used the International Disease Codes to identify 75,100 patient discharges with primary diagnosis code of breast cancer and coincident procedure code for breast surgery from 2005 to 2009. They also acquired information about demographics, hospital characteristics, comorbidities, stage, surgical treatment, postoperative complications and inpatient death.
The investigators used multivariate logistic regression analyses to assess risk-adjusted association between race and patient outcomes.
Patient demographics included 58.3% white, 8.6% black, 5.7% Hispanic, 2.6% Asian and 24.8% identified as “other.”
Compared with whites, blacks were 1.3 times more likely to undergo breast-conserving surgery, and Hispanics were 1.2 times more likely to undergo breast-conserving surgery (P<.001 for both). Asians were less likely to undergo breast-conserving surgery (P<.01).
Blacks were 1.35 times more likely to develop postoperative complications (P<.001) and 1.87 times more likely to experience in-hospital mortality (P<.13).
Also, compared with whites, blacks were 1.17 times more likely to exhibit regional or metastatic disease (P<.001) and 1.58 times more likely to present with comorbidities (P<.003).
For more information:
Dehal A. Abstract #66. Presented at: 2012 Breast Cancer Symposium; Sept. 13-15, 2012; San Francisco.
Disclosure: The researchers report no relevant financial disclosures.