Stomach/Duodenum

Top Story

Novel acid blocker prevents GI ulcers in aspirin, NSAID users

December 12, 2017

Two new studies published in Gut showed that the novel acid blocker vonoprazan effectively prevented ulcer recurrence in aspirin and NSAID users, and thus has the potential to become a new treatment option.

Vonoprazan (Takeda) is a potassium-competitive acid blocker approved in Japan for the treatment of acid-related diseases, with several clinical advantages over PPIs, according to Takashi Kawai, MD, of the endoscopy center at Tokyo Medical University Hospital, and colleagues. “For example, vonoprazan does not require an acidic environment for activation and is acid stable, eliminating the need for an enteric-coated formulation,” they wrote. Additionally, it works faster, and “provides potent and long-lasting inhibition of gastric acid secretion, and its efficacy is therefore expected to be superior to that of PPIs.”

In the Journals Plus

Survey: Physicians rate weight-loss medications, surgery less effective than lifestyle in obesity management

December 11, 2017
Primary care physicians and obesity medicine specialists rated behavioral factors as a greater cause of weight gain vs. biological factors, and rated weight-loss…
In the Journals Plus

STAMPEDE: 5 years after bariatric surgery, increased testosterone levels persist

December 6, 2017
Men with obesity and poorly controlled type 2 diabetes randomly assigned to bariatric surgery saw a near 50% increase in free testosterone that persisted 5 years after…
In the Journals Plus

Long-term weight loss, diabetes remission maintained after RYGB

December 6, 2017
Adults with obesity who underwent Roux-en-Y gastric bypass were likely to maintain much of their weight loss with variable weight fluctuations long term, according to…
More Headlines »
ABIM MOC CME

Ace the Case: 32-Year-Old Male Originally Diagnosed with Chronic Hepatitis C Virus (HCV) genotype 1a (G1a) in 2012 and Relapsed

No commercial support for this activity.

This “Ace the Case” activity will discuss the treatment of a patient originally diagnosed with chronic hepatitis C…
More »
GI Bookshelf

Chapter 5: Dysplasia And Colorectal Cancer

From Clinical Challenges and Complications of IBD
More »
Resource Centers
Advances in IBD

Advances in IBD

Video
Meeting News

VIDEO: Insulin therapy unnecessary more than 5 years after bariatric surgery

November 7, 2017
More »
Advertisement
Advertisement