Pancreatic Disorders

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Familial Chylomicronemia Syndrome: Cause, Effect, and Solutions to Improve Patients’ Quality-of-Life

Healio Gastroenterology, June 2017

Familial chylomicronemia syndrome (FCS) is a rare and potentially life-threatening genetic disease. The clinical hallmark of FCS is pancreatitis associated with marked chylomicronemia and triglyceridemia. It is important that gastroenterologists recognize the signs and symptoms to properly evaluate, as well as manage, patients with FCS. In this activity, a gastroenterologist will review the diagnosis, assessment, management, ongoing challenges, and future therapeutic options for patients with FCS.

Upon successful completion of this educational activity, participants should be better able to:

  • Assess the burden of FCS, its pathophysiology, and the importance of early diagnosis and treatment.
  • Describe the clinical symptomatology associated with FCS, as well as diagnostic modalities that assist in earlier diagnosis.
  • Evaluate the use of dietary modifications for the management of FCS based on efficacy and impact on patient quality-of-life.
  • Recognize the benefits and limitations of available and emerging therapeutic interventions for the management of FCS.

FDA News

FDA grants fast-track status to novel acute pancreatitis therapy

May 30, 2017
The FDA has issued fast-track designation to CM4620, a calcium release-activated calcium channel inhibitor for the treatment of acute pancreatitis, for which there are…
In the Journals

Early feeding may improve outcomes in patients with acute pancreatitis

May 17, 2017
Limited evidence suggests that early enteral feeding for patients hospitalized with mild-to-moderate acute pancreatitis may reduce length of hospital stay and…
In the Journals

ACS model predicts pancreatic fistula risk before surgery

April 19, 2017
Researchers have developed a modified Fistula Risk Score based on data from the American College of Surgeons National Surgical Quality Improvement Program, or NSQIP…
CME

HCV Updates and Case Challenges for the Rapidly Changing Landscape

This activity is supported by an educational grant from Merck & Co., Inc.

In the past few years, significant progress has been made in the treatment of chronic hepatitis C virus (HCV). Highly…
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GI Bookshelf

Chapter 14: Nutrition In The Elderly

From Clinical Nutrition in Gastrointestinal Disease
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Featured
Digestive Disease Week

Digestive Disease Week

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Meeting News Coverage

VIDEO: Cholangioscopy, pancreatoscopy advances improve management of biliary, pancreatic disorders

May 22, 2016
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Education Lab

Familial Chylomicronemia Syndrome: Cause, Effect, and Solutions to Improve Patients’ Quality-of-Life

Healio Gastroenterology, June 2017
Familial chylomicronemia syndrome (FCS) is a rare and potentially life-threatening genetic disease. The clinical hallmark of FCS is pancreatitis…

FDA News

FDA grants fast-track status to novel acute pancreatitis therapy

May 30, 2017
The FDA has issued fast-track designation to CM4620, a calcium release-activated calcium channel inhibitor for the treatment of acute pancreatitis…

In the Journals

Early feeding may improve outcomes in patients with acute pancreatitis

May 17, 2017
Limited evidence suggests that early enteral feeding for patients hospitalized with mild-to-moderate acute pancreatitis may reduce length of hospital…

Feature Article

An Update on Pediatric Pancreatitis

Pediatric Annals, May 2017, Volume 46 Issue 5
There has been a rise in the incidence and number of admissions of children with pancreatitis over the past 20 years. Current management practices…

In the Journals

ACS model predicts pancreatic fistula risk before surgery

April 19, 2017
Researchers have developed a modified Fistula Risk Score based on data from the American College of Surgeons National Surgical Quality Improvement…

Guest Commentary: New treatment reduces triglyceride levels in familial chylomicronemia syndrome

April 7, 2017
In this guest commentary, Andres Gelrud, MD, associate professor of medicine at University of Chicago Medicine, discusses an investigational drug

In the Journals

Cholecystectomy may be unnecessary in some pancreatitis patients

April 6, 2017
Researchers observed “unexpectedly high” adherence to guidelines recommending cholecystectomy within 4 weeks for acute biliary…

In the Journals

Cellvizio accurately diagnoses pancreatic cysts

March 28, 2017
Endoscopic ultrasound-guided needle-based confocal laser endomicroscopy using the Cellvizio platform characterized pancreatic cysts with high…

In the Journals

Long-term corticosteroids may prevent relapse in autoimmune pancreatitis

March 21, 2017
Patients with autoimmune pancreatitis who received maintenance therapy with a low dose of corticosteroids for 3 years showed lower relapse rates and…

FDA News

FDA warns IBS drug Viberzi may cause severe pancreatitis in patients without gallbladder

March 16, 2017
The FDA has issued a safety announcement warning that Viberzi should not be used in patients who do not have a gallbladder due to an increased risk…

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