In the Journals

Almost 16% of pediatric transplant recipients hospitalized with vaccine-preventable diseases

January 15, 2019
Children receiving solid organ transplants — especially lung, heart, intestine and multivisceral transplants — are hospitalized with…
In the Journals

Childhood-onset IBD may be a more aggressive form of disease

January 15, 2019
Insight into immunomodulator and biologic use by patients with inflammatory bowel disease might reveal differences between childhood- and adult-onset…
In the Journals

Nurse-led HCV care model results in 95% or higher SVR rates in prison

January 15, 2019
A decentralized, nurse-led model of hepatitis C care with direct-acting antivirals was significantly effective and led to high levels of sustained…
Meeting News

Pembrolizumab reduces mortality risk in advanced PD-L1-positive esophageal cancer

January 15, 2019
Pembrolizumab significantly improved OS compared with chemotherapy as second-line treatment for patients with advanced or metastatic esophageal or…
In the Journals

Anaerobically prepared FMT may be an effective ulcerative colitis treatment

January 15, 2019
Fecal microbiota transplantation suspensions prepared anaerobically could be an effective treatment for mild-to-moderate ulcerative colitis…
FDA News

FDA approves Cabometyx for treatment-experienced patients with HCC

January 15, 2019
Exelixis has announced it has received FDA approval for Cabometyx to treat patients with hepatocellular carcinoma who previously underwent treatment…
In the Journals

Reverse switch from biosimilar to Remicade produces similar IBD outcomes

January 14, 2019
Patients with inflammatory bowel disease who switched from biosimilar infliximab to Remicade experienced similar results regarding remission, trough…
In the Journals

Stress, environment key barriers to Mediterranean diet uptake for NAFLD

January 14, 2019
Barriers to initiating a Mediterranean diet — shown to improve liver health in patients with nonalcoholic fatty liver disease — included…

ChemomAb doses first patient in phase 1 NAFLD trial

January 14, 2019
ChemomAb dosed the first patient in a phase 1b repeated-dose clinical trial of CM-101 for treating patients with nonalcoholic fatty liver disease and…
In the Journals

Medicare Part D could save $14.4B using VA drug prices

January 14, 2019
If Medicare Part D paid prices for prescription medications similar to what the Department of Veterans Affairs pays, there could be an estimated…
In the Journals

Rise of anti-TNF means less resections in pediatric IBD

January 14, 2019
Since anti-TNF alpha therapy for inflammatory bowel disease was introduced, there has been a significant drop in surgical resections in pediatric…

Study of varlitinib for first-line gastric cancer treatment misses primary endpoint

January 14, 2019
A phase 2 study designed to compare varlitinib with placebo as first-line treatment for certain patients with gastric cancer failed to meet its…
Perspective

HHS task force outlines best practices for pain management, seeks input

January 14, 2019
The Pain Management Best Practices Inter-Agency Task Force — an entity within HHS — recently issued a 91-page report detailing best…

First patient enrolled in pancreatic cancer study

January 12, 2019
The Henry Ford Cancer Institute has announced that it has enrolled the first patient in a new trial to test the effectiveness of precise, higher dose…
In the Journals Plus

Organ-sparing treatment strategy appears promising in early-stage rectal cancer

January 11, 2019
Neoadjuvant chemoradiotherpy followed by transanal endoscopic microsurgery may be a viable alternative to conventional total mesorectal excision for…

NASH update: 6 recent reports on treatment development

January 11, 2019
Researchers continue efforts to study and develop safe and effective therapeutics to treat nonalcoholic fatty liver disease and its progressive form…
Feature

Price hikes on older, brand-name drugs share blame for surging drug costs

January 11, 2019
The pharmaceutical industry, in recent years, has been marked by a cycle of outrage from patient groups, insurers and politicians each time a…
In the Journals

Fecal transplantation, vancomycin superior for recurrent C. diff

January 11, 2019
A combination of fecal microbiota transplantation and vancomycin was superior to fidaxomicin or vancomycin alone for the treatment of recurrent…
In the Journals

Higher intakes of fiber, whole grains protect against noncommunicable diseases

January 11, 2019
Consuming high amounts of dietary fiber and whole grains was associated with reduced risk for noncommunicable diseases, such as coronary heart…
In the Journals

Colon, rectal cancer mortality rates projected to decrease in most countries by 2035

January 11, 2019
Colon and rectal cancer mortality rates are projected to decrease by the year 2035 in most countries across the globe except some countries in Latin…