Motility

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Imodium abuse increasing in US as opioid users seek alternatives

June 22, 2017

Opioid users in the U.S. are increasingly abusing the over-the-counter anti-diarrheal drug loperamide, commonly sold under the trade name Imodium, following the restriction of medications containing hydrocodone in response to the opioid epidemic.

Loperamide toxicity can lead to gastrointestinal, respiratory and neurological problems, and potentially fatal cardiac arrhythmias, which cannot be reversed by naloxone like other opioid overdoses, according to a press release. Young adult men with a history of substance abuse are at the highest risk, and investigators have called for health care professionals to increase their awareness of the potential for loperamide abuse.

First patients receive EndoStim implants in clinical trial for GERD

June 16, 2017
The first patients enrolled in the LESS GERD trial have been implanted with the EndoStim device, a minimally invasive implant that uses neurostimulation to normalize…
In the Journals

Study finds no link between PPIs, dementia, Alzheimer’s risk

June 9, 2017
Researchers found no association between the use of proton pump inhibitors and the risk for mild cognitive impairment, dementia and Alzheimer’s disease in a recent…
FDA News

FDA accepts application to add IBS-C indication for Trulance

June 7, 2017
The FDA has accepted Synergy Pharmaceuticals’ supplemental new drug application to add constipation-predominant irritable bowel syndrome as an indication for…
CME Video

Loss of Response in the Treatment of Crohns Disease: A Case Study

This activity is supported by an educational grant from Receptos.

Anti-TNF agents are effective for inducing and maintaining remission in patients with Crohn's disease. However, a…
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GI Bookshelf

Chapter 53: Nutritional Support Of Obese And Bariatric Patients

From Clinical Nutrition in Gastrointestinal Disease
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Digestive Disease Week

Digestive Disease Week

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Meeting News Coverage

VIDEO: Stretta comparably effective in difficult-to-treat GERD patients

June 2, 2016
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In the Journals

Imodium abuse increasing in US as opioid users seek alternatives

June 22, 2017
Opioid users in the U.S. are increasingly abusing the over-the-counter anti-diarrheal drug loperamide, commonly sold under the trade name Imodium…

First patients receive EndoStim implants in clinical trial for GERD

June 16, 2017
The first patients enrolled in the LESS GERD trial have been implanted with the EndoStim device, a minimally invasive implant that uses…

In the Journals

Study finds no link between PPIs, dementia, Alzheimer’s risk

June 9, 2017
Researchers found no association between the use of proton pump inhibitors and the risk for mild cognitive impairment, dementia and Alzheimer’s…

FDA News

FDA accepts application to add IBS-C indication for Trulance

June 7, 2017
The FDA has accepted Synergy Pharmaceuticals’ supplemental new drug application to add constipation-predominant irritable bowel syndrome as an…

FDgard rapidly improves functional dyspepsia symptoms

May 17, 2017
CHICAGO — FDgard, a medical food containing caraway oil/l-Menthol designed to help manage functional dyspepsia, showed symptom reduction and…

Meeting News

Linx more effective than PPIs for treating regurgitation in GERD

May 15, 2017
CHICAGO — Magnetic sphincter augmentation using the Linx device was more effective than proton pump inhibitor therapy for treating…

FDA News

FDA clears new Endoflip system for assessing motility disorders

May 12, 2017
The FDA has granted 510(k) clearance to the endoscopic diagnostics company Crospon for its new Endoflip system with Flip Topography Module, which…

Meeting News

Relamorelin reduces symptoms in diabetic gastroparesis

May 8, 2017
CHICAGO — Data from a study of patients with diabetic gastroparesis showed that relamorelin reduced symptoms; however, data also showed the…

Meeting News

Acid exposure predicts pulmonary decline after lung transplant

May 6, 2017
CHICAGO — Increased acid exposure time on reflux testing before lung transplantation predicts decline in pulmonary function after…

Meeting News

Trajectory of pH monitoring helps characterize patients non-responsive to PPIs

May 6, 2017
CHICAGO — Trajectory analysis of wireless pH monitoring can help guide diagnosis and management of patients with GERD who do not respond to…

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