Intestinal Disorders

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Novel acid blocker prevents GI ulcers in aspirin, NSAID users

December 12, 2017

Two new studies published in Gut showed that the novel acid blocker vonoprazan effectively prevented ulcer recurrence in aspirin and NSAID users, and thus has the potential to become a new treatment option.

Vonoprazan (Takeda) is a potassium-competitive acid blocker approved in Japan for the treatment of acid-related diseases, with several clinical advantages over PPIs, according to Takashi Kawai, MD, of the endoscopy center at Tokyo Medical University Hospital, and colleagues. “For example, vonoprazan does not require an acidic environment for activation and is acid stable, eliminating the need for an enteric-coated formulation,” they wrote. Additionally, it works faster, and “provides potent and long-lasting inhibition of gastric acid secretion, and its efficacy is therefore expected to be superior to that of PPIs.”

In the Journals

Fatty liver index useful for predicting precancerous colon polyps

December 11, 2017
Patients with a high fatty liver index, a noninvasive method used to predict non-alcoholic fatty liver disease, showed a higher risk for colorectal adenomas, according…
In the Journals

Diverticulitis risk lower among men with healthy lifestyle

November 30, 2017
Men who led a healthy lifestyle, including those who limited their red meat intake, ate higher levels of dietary fiber, exercised, maintained a healthy weight and…
Meeting NewsVideo

VIDEO: Diverticular disease deserves more awareness in GI

October 17, 2017
ORLANDO — Despite diverticulitis being viewed as the realm of surgeons or internists, there are new data that gastroenterologists need to understand, according to…
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ABIM MOC CME

Ace the Case: 32-Year-Old Male Originally Diagnosed with Chronic Hepatitis C Virus (HCV) genotype 1a (G1a) in 2012 and Relapsed

No commercial support for this activity.

This “Ace the Case” activity will discuss the treatment of a patient originally diagnosed with chronic hepatitis C…
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GI Bookshelf

Question 43: Caroli's Disease, What Do I Need to Know?

From Curbside Consultation of the Pancreas: 49 Clinical Questions
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Resource Centers
Advances in IBD

Advances in IBD

Video
Meeting News Coverage

VIDEO: Several new drug treatments benefit patients with IBS

June 4, 2015
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