WASHINGTON — Men with inflammatory bowel disease are more likely to have impaired sexual dysfunction according to findings from a study presented during Digestive Disease Week.
“The symptoms of IBD, disease complications and treatments impair body image, sexual function and intimacy,” Aoibhlinn M. O’Toole, MD, a clinical fellow in the IBD Center at Beth Israel Deaconess Medical Center and the Brigham and Women’s Hospital in Boston, said during her presentation. “Despite the clear significance of these issues, the knowledge and extent of the impact is scarce.”
O’Toole and colleagues, conducted the study to assess the prevalence of sexual dysfunction in men with IBD and to try to identify the causal or associative factors that could be treatable or preventable.
With no available questionnaire specific to IBD, the researchers developed a novel IBD-specific questionnaire. The end result was a 43-question survey called the IBD sexual dysfunction scale (IBD-SDS). The investigators also included a validated sexual function tool (the international index of erectile function, or IIEF) and a validated depression screening tool (patient health questionnaire-9, or PHQ-9).
A total of 156 adult men who attended IBD clinics at either Beth Israel Deaconess Medical Center or Brigham and Women’s Hospital in Boston. From that cohort, 57.7% of the patients had Crohn’s Disease and 42.3% had ulcerative colitis. The mean age of the population was 42 years (range, 20-84). A total of 87% of the men reported being in a relationship that could involve sexual activity and 70% reported being married or in a long-term relationship. Additionally, 2% of the patients reported not being sexually active in the past year.
The data showed that 20% of the patients reported they were hesitant to start a new relationship because of their IBD and 7.8% reported that IBD was responsible in some way for the breakup of an existing relationship.
Additionally, 38% reported that IBD affected their desire to engage in sexual activity, 26% said that IBD specifically prevented them from having sex, 18% reported IBD caused problems during sex and 20% reported IBD made them feel guilty about sex.
Using the PHQ-9 as a measure, the patients deemed to have moderate to severe depression had lower sexual satisfaction scores (P < .0001) and that they had a harder time keeping their erections (P = .0047).
Patients who had ostomies did have higher scores on PHQ-9 than those patients who had no prior surgery (P = .0095), greater difficulty getting (P < .0001) or keeping an erection (P = .0001) and poorer quality of erections (P = .0002). Additionally, patients with peri-anal disease reported higher rates of premature ejaculation (P = .0440).
Patient’s with Crohn’s disease who had a Harvey-Bradshaw Index score of greater than 5 were significantly less-satisfied with their sex life scores (P = .0152), had more difficult getting an erection (P = 0.0245) and had a poorer quality of erections (P = .0049).
Patients with ulcerative colitis and a simple clinical colitis activity index scores greater than 4 had higher PHQ-9 scores (P = .0025) but there was no difference in their sexual function scores.
Those patients aged 50 years or older had lower sexual satisfaction scores (P = .0214) reported greater difficulty getting erections (P = .0042) and keeping them (P = .0007) and poorer quality of their erections (P < .0001).
Using the IIEF alone to analyze the data, all of the results reported were considered statistically significant. – by Anthony SanFilippo
For more information: O’Toole, AM, et al. Presentation #151. Presented at: Digestive Disease Week; May 15-19, 2015; Washington, D.C.
Disclosure: O’Toole reports no relevant financial disclosures. See the faculty disclosure index on the DDW website for a full list of disclosures.