Inflammatory Bowel Disease

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AGA releases guideline on therapeutic drug monitoring in IBD

August 16, 2017

The AGA has issued new guideline recommendations on therapeutic drug monitoring in patients with inflammatory bowel disease treated with anti-TNF agents and thiopurines.

The guideline also includes recommendations for thiopurine methyltransferase (TPMT) enzyme measurement or genotyping before starting a thiopurine, but does not address therapeutic drug monitoring in patients treated with Entyvio (vedolizumab, Takeda) or Stelara (ustekinumab, Janssen) due to a lack of available data.

NIH awards $1.83 million to advance IBD research

August 15, 2017
A researcher at the University of California, Riverside has received a four-year, $1.83 million grant from the NIH to determine how the loss of a protective barrier in…
In the Journals

Fecal calprotectin performs best for diagnosing children with IBD symptoms

August 15, 2017
Among common laboratory markers used in the diagnostic workup of children with symptoms of inflammatory bowel disease in hospital settings, fecal calprotectin improved…

Pan-JAK inhibitor for UC shows signs of targeted action in early study

August 10, 2017
Theravance Biopharma’s oral, intestinally-restricted pan-Janus kinase inhibitor has shown signs of localized target engagement in an ongoing phase 1b trial of…
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CME Video

Loss of Response in the Treatment of Crohns Disease: A Case Study

This activity is supported by an educational grant from Receptos.

Anti-TNF agents are effective for inducing and maintaining remission in patients with Crohn's disease. However, a…
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GI Bookshelf

Chapter 6: Nutrients To Nourish The Organisms: Prebiotics And Fiber

From Probiotics: A Clinical Guide
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Resource Centers
Biosimilars in the US

Biosimilars in the US

Video
Meeting News

VIDEO: Speaker reviews factors that impact response to treatment for Crohn’s disease, ulcerative colitis

March 28, 2017
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