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New drug effective, well tolerated in patients with osteoarthritis knee pain

September 8, 2017

In patients with moderate to severe osteoarthritis knee pain, a single intra-articular injection of 1 mg of CNTX-4975 was well tolerated and significantly improved pain with walking, knee stiffness and physical function, according to findings presented at PAINWeek.

“As our populations are aging, the number of people suffering from moderate to severe knee osteoarthritis is increasing,” Randall M. Stevens, MD, chief medical officer of Centrexion Therapeutics, told Healio Internal Medicine. “Unfortunately, current treatments — like NSAIDs, opioids or hyaluronic acid and corticosteroid injections — are limited in the level of efficacy they provide, and come with significant side effects that can be serious, especially in older individuals. CNTX-4975 for intra-articular injection has shown substantial promise in clinical trials as a long-lasting and efficacious treatment, with a safety profile that looks similar to that of placebo.”

Yoga as medicine: What PCPs need to know

September 1, 2017
September is designated by HHS as National Yoga Awareness Month with the intention of educating people on the benefits of yoga to inspire a healthier lifestyle…
FDA News

FDA approves Humira biosimilar Cyltezo

August 28, 2017
The FDA has approved the second biosimilar to Humira, Cyltezo, for several gastroenterological, rheumatological and dermatological indications. Cyltezo (adalimumab-adbm…

What you should know about osteoarthritis

August 14, 2017
Osteoarthritis, also known as degenerative joint disease, occurs when the cartilage that covers the end of joints breaks down. This loss of cartilage results in pain…
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Giant Cell Arteritis: The Promise of Earlier Diagnosis and Targeted Therapy

This activity is supported by an educational grant from Genentech, Inc.

Early diagnosis of giant cell arteritis is critical to preventing blindness and other complications of this potentially…
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GI Bookshelf

Chapter 53: Nutritional Support Of Obese And Bariatric Patients

From Clinical Nutrition in Gastrointestinal Disease
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Resource Centers
American Association of Nurse Practitioners National Conference

American Association of Nurse Practitioners National Conference

Meeting News Coverage

VIDEO Rigby discusses oncology therapies and autoimmune diseases

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