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Experts revise PANS/PANDAS treatment guidelines

July 25, 2017

A panel of clinicians and researchers recently published revised treatment recommendations for management of Pediatric Acute Onset Neuropsychiatric Syndrome and Pediatric Autoimmune Neuropsychiatric Syndrome Associated with Streptococcal Infection.

“Directly controlling or minimizing symptoms of [Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS)/Pediatric Autoimmune Neuropsychiatric Syndrome Associated with Streptococcal Infection (PANDAS)] is essential to decrease suffering, increase the child’s ability to receive other important treatments, and overall recovery. As is true in treatment of delirium, the instigating processes (which include infections and inflammatory diseases) and symptoms of PANS/PANDAS must be addressed simultaneously,” Margo Thienemann, MD, of Stanford University, and colleagues wrote. “Early research in other types of brain injury, including concussion, stroke, and multiple sclerosis, suggest that neural plasticity depends on use and that early rehabilitation has better outcome, supporting the prompt initiation of psychotherapy.”

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