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Transition to denosumab monotherapy after combination results in favorable BMD changes

June 22, 2017

Postmenopausal women with osteoporosis who switched from combination denosumab therapy to denosumab monotherapy experienced the most favorable total and cortical volumetric bone mineral density changes compared with switching from denosumab to teriparatide or from teriparatide to denosumab.

Joy N. Tsai, MD, of the endocrine unit at Massachusetts General Hospital, and colleagues evaluated data from 679 postmenopausal women with osteoporosis to determine the effect on BMD of switching from teriparatide (Forteo, Eli Lilly) to denosumab as part of the DATA-Switch HR-pQCT study.

In the Journals

ED visits, cost associated with shingles increase

June 22, 2017
Emergency department visits and total cost associated with herpes zoster increased between 2006 and 2013, driven by an increased number of visits by patients aged 20 to…
In the Journals

Microvascular dysfunction may increase risk for late-life depression

June 22, 2017
Peripheral and cerebral forms of microvascular dysfunction were associated with increased risk for depression, according to recent findings. “Evidence suggests a…

Q&A: Treating patients with Alzheimer’s and their caregivers

June 20, 2017
Alzheimer’s and Brain Awareness Month is annually observed in June to raise awareness for the disease that currently affects more than 5 million Americans, and may…
CME
Redefining the Management of Parkinson's Disease Psychosis: A Meeting of the Minds

Redefining the Management of Parkinson's Disease Psychosis: A Meeting of the Minds

This activity is supported by an educational grant from Acadia Pharmaceuticals, Inc.

The motor symptoms associated with Parkinson's disease (PD) are well recognized, but the non-motor symptoms are…
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GI Bookshelf
Chapter 6: Nutrients To Nourish The Organisms: Prebiotics And Fiber

Chapter 6: Nutrients To Nourish The Organisms: Prebiotics And Fiber

From Probiotics: A Clinical Guide
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Pediatric Academic Societies Annual Meeting

Pediatric Academic Societies Annual Meeting
Video
Meeting News Coverage
VIDEO: IBD specialist recaps presentation on caring for elderly IBD patients

VIDEO: IBD specialist recaps presentation on caring for elderly IBD patients

December 12, 2015
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In the Journals PlusPerspective

Transition to denosumab monotherapy after combination results in favorable BMD changes

June 22, 2017
Postmenopausal women with osteoporosis who switched from combination denosumab therapy to denosumab monotherapy experienced the most favorable total…

In the Journals

ED visits, cost associated with shingles increase

June 22, 2017
Emergency department visits and total cost associated with herpes zoster increased between 2006 and 2013, driven by an increased number of visits by…

In the Journals

Microvascular dysfunction may increase risk for late-life depression

June 22, 2017
Peripheral and cerebral forms of microvascular dysfunction were associated with increased risk for depression, according to recent findings…

Q&A: Treating patients with Alzheimer’s and their caregivers

June 20, 2017
Alzheimer’s and Brain Awareness Month is annually observed in June to raise awareness for the disease that currently affects more than 5…

In the Journals
Teemu J. Niiranen, MD, PhD

Healthy vascular aging possible with favorable lifestyle

June 20, 2017
Healthy arterial aging is possible in adults younger than 70 years, despite confounding factors of a Western lifestyle, so targeting modifiable…

In the Journals

Mental illness increases risk for discharge against medical advice

June 19, 2017
Certain factors, including mental illness, race, low income and being uninsured, were associated with a heightened risk for deciding to leave the…

In the JournalsPerspective

Long-term aspirin use in older patients increases risk for major bleeding

June 14, 2017
Patients who had an MI, transient ischemic attack or ischemic stroke and received aspirin-based antiplatelet treatment without proton pump inhibitors…

In the Journals

PCP-based skin cancer screening feasible

June 13, 2017
Primary care-based skin cancer training and screening is feasible, and may improve primary care physician diagnostic accuracy, according to recently…

In the Journals

Neuropsychological measures useful for detecting preclinical Alzheimer's disease

June 13, 2017
Neuropsychological measures demonstrated utility for detecting preclinical Alzheimer’s disease among older adults, according to study…

In the Journals

Keytruda treatment may be associated with eruptive keratoacanthomas

June 12, 2017
Keytruda therapy was associated with eruptive keratoacanthomas in three patients with metastatic squamous cell carcinoma or metastatic melanoma…

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