September 18, 2017
Patients with type 2 diabetes but without existing cardiovascular disease experienced a time-dependent increase in platelet aggregation in the 24 hours after once-daily aspirin therapy, suggesting that a twice-daily aspirin regimen could provide CV benefit, study data show.
“The antiplatelet effects of aspirin do not last for the standard 24-hour dosing interval, and patients with type 2 diabetes have alterations in their platelet function,” Liv Vernstrøm, a master’s student in the department of endocrinology and internal medicine at Aarhus University in Denmark, told Endocrine Today. “Perhaps the alterations seen in platelet function in patients with type 2 diabetes could be related to their increased risk for CVD. Further, they might benefit from an alternative dosing regimen when it comes to treatment with aspirin. Our data indicate that a twice-daily dosing could add additional benefits, but this needs to be studied further.”