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Opioid abuse treatment medications equally effective

November 15, 2017

Buprenorphine-naloxone combination and extended-release naltrexone were both safe and effective in managing patients with opioid use disorder, yielding nearly identical results, according to findings recently published in The Lancet.

“Previous opioid antagonist or agonist comparisons have evaluated oral naltrexone and long-term naltrexone implants, but not monthly extended-release naltrexone treatment,” Joshua D. Lee, MD, department of population health, New York University School of Medicine, and colleagues wrote. “Important clinical issues remain unanswered, beyond the established efficacy of either extended-release naltrexone or buprenorphine-naloxone.”

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