Addiction

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Monthly buprenorphine depot RBP-6000 effective, safe for opioid addiction

June 23, 2017

Indivior recently presented phase 3 findings that indicated efficacy and safety of RBP-6000, an investigational once-monthly injectable buprenorphine in the Atrigel delivery system, for treatment of moderate-to-severe opioid use disorder.

“The clinical data from our phase 3 study also showed that outcomes with RBP-6000 are consistent across other secondary clinical endpoints, including control of craving and withdrawal symptoms, as compared to placebo,” Christian Heidbreder, PhD, chief scientific officer of Indivior, said in a press release. “These outcomes started with the first dose of RBP-6000, which achieved buprenorphine plasma concentrations 2 ng/mL and predicted whole brain µ-opioid receptor occupancy of 70%, and were also maintained for the 1-month dosing intervals and for the entire treatment duration.”

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Meeting News

Monthly buprenorphine depot RBP-6000 effective, safe for opioid addiction

June 23, 2017
Indivior recently presented phase 3 findings that indicated efficacy and safety of RBP-6000, an investigational once-monthly injectable buprenorphine…

Meeting News

Patient engagement is critical to treat chronic pain, opioid use disorder

June 22, 2017
PHILADELPHIA —  Successfully treating patients with chronic pain and opioid use disorder must involve the patient being actively engaged…

In the Journals

Pregnancy has protective effect on drug abuse

June 20, 2017
Risk for drug abuse was substantially lower during pregnancy, suggesting a potential protective effect, according to recent findings. “The…

Meeting News

AMA supports efforts to combat ‘dangerous’ synthetic, injectable drugs

June 13, 2017
AMA delegates at the annual meeting underway in Chicago voted to back several efforts to close a gap in the nation’s ability to identify…

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