Top Story

Preliminary findings show safety of intranasal OPNT002 for alcohol addiction

July 25, 2017

Opiant Pharmaceuticals Inc. recently announced phase 1 data showing efficacy and safety of OPNT002, intended for treatment of alcohol use disorder, among healthy individuals.

“We are very excited by the observed changes in the pharmacokinetic properties of intranasal naltrexone when combined with Intravail, particularly the ability of Intravail to reduce the time needed to reach maximum plasma concentrations, which implies a more rapid onset of action,” Phil Skolnick, PhD, DSc, chief scientific officer at Opiant Pharmaceuticals Inc., said in a press release. “Although additional clinical work is required, the ability to rapidly deliver an intranasal dose of naltrexone on an ‘as needed’ basis has the potential to offer patients a much-needed innovation in the treatment of [alcohol use disorder].”

In the Journals

Intervention improves guideline adherence, does not decrease opioid refills

July 19, 2017
A multicomponent primary care-based intervention tripled guideline-concordant opioid monitoring; however, it was not successful in reducing opioid misuse risk, according…

CDC awards $12 million toward opioid epidemic

July 18, 2017
The CDC recently awarded more than $12 million in funding for the opioid epidemic to 23 states and Washington, D.C. “The opioid epidemic is a scourge on our nation…
In the Journals

Opioid dose reduction may benefit patients with chronic pain

July 17, 2017
Reducing or discontinuing long-term opioid therapy may improve pain, function and quality of life among patients with chronic pain; however, these findings are supported…
More Headlines »

Ethics and Professional Boundaries in Healthcare

No commercial support for this activity.

This course focuses on ethical theory, principles, and models for decision making that are most applicable for those…
More »
GI Bookshelf

Question 14: Why is Bloating Such a Problem in Patients With IBS?

From Curbside Consultation in IBS: 49 Clinical Questions
More »
Resource Centers
American Association of Nurse Practitioners National Conference

American Association of Nurse Practitioners National Conference

Meeting News Coverage

VIDEO: Leone: FDA regulating e-cigarettes reduces ‘potential for harm;’ ACP applauds decision

May 7, 2016
More »