Varying PD-practices between different regions impacted volume status, according to a published study. In addition, volume overload — present even before the start of kidney replacement therapy — was associated with specific patient characteristics and higher mortality risk.
“It is postulated that the active management of volume overload may reduce risk of technique failure (transfer to hemodialysis) and improve survival in PD patients,” Wim Van Biesen, MD, PhD, of the department of internal medicine, renal division, at University Hospital Ghent in Belgium, and colleagues wrote. “However, most of the strategies used to reduce volume overload also carry a risk for undesired side effects. It is thus also important to take into account the strategies used to maintain euvolemia. With this in mind, the Initiative for Patient Outcomes in Dialysis-Peritoneal Dialysis (IPOD-PD) study investigates volume status in an incident patient population to relate patient characteristics and practice patterns over a long-term follow-up to volume status and patient relevant outcomes.”
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