Endocrinology

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Experimental oral diabetes drug appears safe, effective in Japanese adults

September 23, 2017

Imeglimin, part of a new class of oral agents for type 2 diabetes that target mitochondrial bioenergetics, was found to be safe and effective in Japanese adults, according to results presented at the European Association for the Study of Diabetes Annual Meeting.

Kohjiro Ueki, MD, PhD, director of the Diabetes Research Center at the National Center for Global Health and Medicine in Tokyo, and colleagues conducted a phase 2b randomized, double-blind, placebo-controlled study of imeglimin in Japanese adults with type 2 diabetes (n = 299). Participants were randomly assigned to one of three doses of twice-daily imeglimin (500 mg, 1000 mg and 1500 mg) or placebo for 24 weeks.

Gurman says, ‘Our voice is their voice’ in explaining the importance of physician advocacy

September 22, 2017
At a time when the state of health care is in flux, it is critical that physicians engage in the national debate by telling their stories and those of their patients to…
In the Journals Plus

Age-related changes in thyroid physiology influence hormone levels

September 22, 2017
Thyroid function is linked with age-related changes in pituitary and thyroid physiology in older adults, according to data recently published in Thyroid.
In the Journals Plus

Strategies needed to engage younger women with National Diabetes Prevention Program

September 22, 2017
Women aged 39 years or younger with prediabetes or past gestational diabetes are half as likely to enroll in a National Diabetes Prevention Program and less likely to…
In the Journals PlusPerspective

Carbohydrate consumption timing affects glucose, insulin excursions

September 22, 2017
Adults with type 2 diabetes who consumed carbohydrates last during their meals had lower glucose peaks and insulin excursions and higher GLP-1 excursions compared with…
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CME

Diabetic Eye 2015: New Concepts in Screening, Managing, and Referral

This activity is supported by an educational grant from Allergan, Inc.

Despite a number of effective treatment options, diabetic eye disease is a leading cause of vision loss in the United…
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VIDEO: Mobile technology valuable option for diabetes education

August 4, 2017
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CME

Practical Lipidology®: Volume 3, Number 2

This activity is supported by an educational grant from Amgen

The reduction of low-density lipoprotein-cholesterol (LDL-C) is recognized as the primary strategy for decreasing…
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