Endocrinology

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Bone score may predict fracture risk in postmenopausal women on bisphosphonate therapy

June 28, 2017

Postmenopausal women with osteoporosis prescribed oral bisphosphonate therapy for at least 4 years were more likely to sustain a fracture if they had a lower bone material strength index score compared with women who did not sustain a fracture, according to findings from a Spanish study.

“Despite advantages and good adherence to therapy, some patients still experience fractures while receiving oral bisphosphonates,” Adolfo Diez-Perez, MD, PhD, of the Hospital del Mar Research Institute in Barcelona, Spain, and colleagues wrote. “Several factors may contribute to the apparent lack of full efficacy, such as low levels of vitamin D, concomitant diseases, very low bone mineral density and advanced deterioration of bone microarchitecture that induces a situation not fully compensated by the beneficial effects of drugs. Therefore, it would be interesting to explore whether bone characteristics at a tissue level can contribute to incident fractures in patients on active treatment.”

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CME

Rapid Response from Austin: Expanding Options in Type 2 Diabetes Management

This activity is supported by educational grants from Boehringer Ingelheim Pharmaceuticals, Inc. and Lilly USA, LLC.

Approximately 150 million people worldwide have diabetes mellitus and this number is expected to double by 2025…
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VIDEO: New NLA president discusses updates to PCSK9 inhibitor recommendations

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The Endocrine Society Annual Meeting

The Endocrine Society Annual Meeting

CME

Improving Bone Strength and Reducing Fracture Risk in Osteoporosis

This activity is supported by an educational grant from Merck & Co., Inc.

Osteoporosis is characterized by low bone mass and microarchitectural deterioration of bone tissue leading to reduced…
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