Early data show beloranib improved hunger-related behaviors in Prader-Willi syndrome

January 17, 2014
An investigational selective inhibitor of methionine aminopeptidase 2, beloranib, has demonstrated significant reductions in body fat, body weight…
In the Journals

MAGEL2 gene could contribute to symptoms of Prader-Willi syndrome, autism

September 30, 2013
Researchers have identified a gene in which a loss of function could contribute to aspects of Prader-Willi syndrome and possibly complex autism…
In the JournalsPerspective

Long-term GH therapy could slow course of Prader-Willi syndrome

September 12, 2013
Results from an 8-year study suggest that growth hormone therapy in children with Prader-Willi syndrome yielded long-term benefits, according to…
In the Journals

Topotecan may be therapeutic for Angelman, Prader-Willi syndrome

August 6, 2013
Recent data suggest that a chemotherapy agent used to treat metastatic cancers may also be therapeutic for Angelman or Prader-Willi syndrome…
In the JournalsPerspective

Recombinant GH appears effective for Prader-Willi syndrome

April 4, 2013
The use of recombinant human growth hormone in patients with Prader-Willi syndrome has been met with concern about potential adverse events. To…
In the JournalsPerspective

GH in childhood decreased BMI in adults with Prader-Willi syndrome

Endocrine Today, February 2013
Several years after treatment was discontinued, researchers have found that growth hormone administered during childhood and adolescence…
In the JournalsPerspective

Children with Prader-Willi at increased risk for congenital defects

Endocrine Today, February 2013
In a recent study, researchers found that children with Prader-Willi syndrome displayed an increased prevalence of congenital defects, including…
In the Journals

Children with Prader-Willi syndrome, obstructive sleep apnea may benefit from adenotonsillectomy

November 21, 2012
Adenotonsillectomy may relieve sleep disorders among children with Prader-Willi syndrome, according to data published in the Archives of
Cover StoryPerspective

Increased awareness, earlier detection bring relief to challenges of Prader-Willi syndrome

Endocrine Today, April 2011
Prader-Willi syndrome is a complex disease to manage, and careful consideration of its unique clinical features is essential. Recently…
Behind the Name

Collaboration of physicians behind first observations of Prader-Willi syndrome

Endocrine Today, October 2008
Andrea Prader and Heinrich Willi, two Swiss pediatricians, and Alexis Labhart, an internist, first described Prader-Labhart-Willi Syndrome in…