Reproduction/Androgen Disorders

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Oral contraceptive plus spironolactone safely addresses androgen excess in PCOS

September 14, 2017

Women with polycystic ovary syndrome treated with a combination oral contraceptive with spironolactone were not at increased risk for metabolic or cardiovascular complications, according to findings published in the European Journal of Endocrinology.

Héctor F. Escobar-Morreale, MD, PhD, of the department of endocrinology and nutrition at Hospital Universitario Ramón y Cajal in Madrid, and colleagues evaluated 46 women with PCOS randomly assigned to metformin (n = 22) or to a combined oral contraceptive (ethinyl estradiol 30 µg and desogestrel 150 µg) plus 100 mg per day of the antiandrogen spironolactone (n = 24) for 1 year to determine efficacy and safety in relation to cardiometabolic risk factors and adverse events.

In the Journals PlusPerspective

Hormone therapy does not increase mortality risk in postmenopausal women

September 12, 2017
All-cause mortality and death rates from cardiovascular diseases, cancer and other causes do not significantly differ among women assigned to receive hormone therapy for…
In the Journals Plus

Urinary gonadotropin levels aid precocious puberty diagnosis

September 12, 2017
Urinary gonadotropin levels increased shortly before the onset of puberty among girls and boys, according to researchers in Denmark. In particular, girls with
In the Journals Plus

High estriol levels protect against breast cancer in pregnancy

September 6, 2017
High levels of estriol may protect pregnant women in their third trimester from breast cancer, whereas elevated levels of estrone and estradiol may increase cancer risk
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Diabetic Retinopathy: The Importance of Early Screening, Referral, and Management

This activity is supported by an educational grant from Regeneron Pharmaceuticals, Inc.

Diabetic eye disease is one of the most common causes of vision loss in the United States. As the rates of diabetes…
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Meeting News Coverage

VIDEO: Wide choice of therapeutic options available for menopause symptoms

March 6, 2015
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Resource Centers

Managing Obesity in 2015: Setting the Framework and Assessing All of the Options

This activity is supported by an educational grant from Novo Nordisk.

This CME activity is based on the slides and lectures presented by the faculty at the symposium, Managing Obesity in…
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