EXPERT SUMMARIES of the top 30 journals in endocrinology
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Vitamin D supplementation fails to improve semen quality in men with infertility

Jensen MB, et al. J Clin Endocrinol Metab. 2017;doi:10.1210/jc.2017-01656.
Vitamin D supplementation did not improve the quality of semen in men with infertility and vitamin D deficiency, a randomized clinical trial found
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Use of advanced functions on insulin pumps improves HbA1c in diabetes

Lepore G, et al. Nutr Metab Cardiovasc Dis. 2017;doi:10.1016/j.numecd.2017.12.001.
HbA1c levels were lower in adults and children with diabetes who use advanced pump functions, have a higher rate of sensor use and who have a longer…
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Short-term melatonin supplementation decreases cardiometabolic risk in type 2 diabetes, CHD

Raygan F, et al. Clin Nutr. 2017;doi:10.1016/j.clnu.2017.12.004.
Adults with type 2 diabetes and coronary heart disease who used melatonin supplementation for 12 weeks experienced improvements in biomarkers for…
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Clinical, behavioral diabetes risk factors high in early onset of disease

Bo A, et al. Diabetes Metab Res Rev. 2017;doi:10.1002/dmrr.2968.
Adults with type 2 diabetes who are diagnosed at age 45 years or younger are more likely to have poor glucose control, increased BMI and dyslipidemia…
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NHANES: Nearly 25% of U.S. veterans have diabetes

Liu Y, et al. Prev Chronic Dis. 2017;doi:10.5888/pcd14.170230.
More than 20% of U.S. veterans have diabetes and 3.4% have undiagnosed diabetes, a combined figure that is more than double the diabetes rate in the…
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Incident type 2 diabetes tied to net excess weight in overweight, central obesity

Zameni F, et al. Diabetes Res Clin Pract. 2017;doi:10.1016/j.diabres.2017.12.002.
The risk for incident type 2 diabetes is associated with the degree and duration of excess waist circumference and excess weight, study data show. …
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Advanced glycation end products, oxidation products tied to CVD risk in type 2 diabetes

Koska J, et al. Diabetes Care. 2017;doi:10.2337/dc17-1740.
Adults with type 2 diabetes may be at increased risk for cardiovascular disease with low levels of the oxidation product methionine sulfoxide and…
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Insulin pump therapy improves glucose control, total insulin dose in type 2 diabetes

Chlup R, et al. Diabetes Technol Ther. 2017;doi:10.1089/dia.2017.0283.
Patients with poorly controlled type 2 diabetes and insulin resistance saw an improvement in glycemic profile and a reduction in total daily insulin…
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Depression not linked with glycemic control in adolescents with type 2 diabetes

VanBuren DJ, et al. Diabetes Res Clin Pract. 2017;doi:10.1016/j.diabres.2017.11.008.
Symptoms of depression were not associated with glycemic control in adolescents with type 2 diabetes, although depression was common, according to
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Once-daily glucocorticoid therapy improves immune, metabolic function in adrenal insufficiency

Isidori AM, et al. Lancet Diabetes Endocrinol. 2017;doi:10.1016/s2213-8587(17)30398-4.
Johannsson G. Lancet Diabetes Endocrinol. 2017;doi:10.1016/s2213-8587(17)30431-x.
Patients with primary or secondary adrenal insufficiency assigned to once-daily hydrocortisone therapy for 24 weeks experienced fewer infections and…
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Low vitamin D level may increase risk for heart failure hospitalization

Costanzo S, et al. Nutr Metab Cardiovasc Dis. 2017;doi:10.1016/j.numecd.2017.11.008.
Adults with a low serum 25-hydroxyvitamin D concentration are more likely to be admitted to the hospital with heart failure and spend more days in…
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Meta-analysis: GLP-1 receptor agonists reduce CV risks in type 2 diabetes

Bethel MA, et al. Lancet Diabetes Endocrinol. 2017;doi:10.1016/S2213-8587(17)30412-6.
Taylor SI. Lancet Diabetes Endocrinol. 2017;doi:10.1016/S2213-8587(17)30413-8.
Adults with type 2 diabetes are effectively treated with GLP-1 receptor agonists compared with placebo and experience significant decreases in…
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HbA1c reductions differ with type of second-line drug class

Gottlieb A, et al. BMJ Open Diabetes Res Care. 2017;doi:10.1136/bmjdrc-2017-000435.
HbA1c is significantly reduced in adults with type 2 diabetes when treated with a second-line drug class, but reductions are greater with…
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Levothyroxine treatment does not alter pregnancy outcomes

Wang H, et al. JAMA. 2017;doi:10.1001/jama.2017.18249.
Miscarriage, intrauterine pregnancy and live-birth rates were not affected with levothyroxine treatment in women who were…
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USPSTF recommends against HT for prevention of chronic conditions in postmenopausal women

Gartlehner G, et al. JAMA. 2017;doi:10.1001/jama.2017.16952.
Hormone therapies in menopausal women are associated with some beneficial effects, such as decreased risk for diabetes and fracture, but are also…

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