EXPERT SUMMARIES of the top 30 journals in endocrinology
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For transgender men, testosterone formulations equally safe, effective

Gava G, et al Clin Endocrinol. 2018; doi:10.1111/cen.13821.
In young transgender men, long-acting testosterone undecanoate and testosterone enanthate were equally effective and safe when administered for 5…
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Testosterone provides safe estrogen alternative for women with complete androgen insensitivity syndrome

Birnbaum W, et al. Lancet Diabetes Endocrinol. 2018; doi:10.1016/s2213-8587(18)30197-9.
Sandberg DE. Lancet Diabetes Endocrinol. 2018: doi: 10.1016/s2213-8587(18)30206-7.
Women with complete androgen insensitivity syndrome randomly assigned to receive daily testosterone therapy for 6 months experienced a marked…
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Thyroid hormone levels associated with body composition parameters in euthyroid adults

Kwon H, et al. Clin Endocrinol. 2018; doi:10.1111/cen.13823.
In euthyroid men and women, higher levels of serum free triiodothyronine are associated with lower skeletal muscle mass index and greater levels of…
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Daily steps, measured by pedometer, may reduce risk for progression to diabetes

Kraus WE, et al. BMJ Open Diabetes Res Care. 2018;doi:10.1136/bmjdrc-2018-000523.
Pedometer-measured physical activity is a valuable approach for reducing risk for progression to diabetes in an at-risk population, according to…
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Gastric bypass surgery associated with increased fracture risk

Axelsson KF, et al. J Bone Miner Res. 2018;doi:10.1002/jbmr.3553.
Adults with obesity who undergo Roux-en-Y gastric bypass surgery are more likely to sustain a fracture independent of the amount of weight loss or
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In-person education, provider training may reduce pediatric intake of sugar-sweetened beverages

Vercammen KA, et al. Obes Rev. 2018;doi:10.1111/obr.12741.
Effective interventions for decreasing consumption of sugar-sweetened beverages among children aged 0 to 5 years often take place in…
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Pharmacotherapy effective weight-loss option in PCOS with obesity

Wang FF, et al. Obes Rev. 2018;doi:10.1111/obr.12720.
The GLP-1 receptor agonist liraglutide, the weight loss drug orlistat and metformin are effective adjuncts to a low-energy diet and increased…
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Single, multi-item measures may better identify disorders of sex development, intersex conditions in population surveys

Tamar-Mattis S, et al. LGBT Health. 2018;doi:10.1089/lgbt.2017.0180.
The use of single- or multi-item measures in population surveys may serve as a useful tool to better account for adults with disorders of sex…
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Sitagliptin improves glycemic profile in type 2 diabetes, mild renal impairment

Scott R, et al. Diabetes Obes Metab. 2018; doi:10.1111/dom.13473.
Adults with type 2 diabetes, mild renal insufficiency and an elevated HbA1c assigned the DPP-IV inhibitor sitagliptin experienced greater
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Women with PCOS report lack of trust, emotional support in primary care

Lin AW, et al. J Endocr Soc. 2018; doi:10.1210/js.2018-00181.
Women with polycystic ovary syndrome are more likely to trust a specialist vs. a primary care provider to treat their PCOS-related concerns and…
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Physical performance measures, appendicular lean mass may predict incident fractures

Harvey NC, et al. J Bone Miner Res. 2018; doi:10.1002/jbmr.3556.
Incident fractures may be predicted by physical performance and appendicular lean mass, independent of previous falls and FRAX probability, according…
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Incident stroke risk increases with rising BMI

Liu X, et al. Nutr Metab Cardiovasc Dis. 2018; doi:10.1016/j.numecd.2018.07.004.
A meta-analysis of more than 4 million adults suggests there is a J-shaped association between BMI and risk for incident stroke, with each 5-unit BMI…
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Glucose level may predict CV risk after noncardiac surgery, regardless of diabetes status

Punthakee Z, et al. Lancet Diabetes Endocrinol. 2018; doi:10.1016/s2213-8587(18)30205-5.
Elevated casual or fasting glucose levels measured before noncardiac surgery may predict risk for myocardial injury and death in the days after…
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New international PCOS guideline aims to streamline care

Teede HJ, et al. Fertil Steril. 2018;doi:10.1016/j.fertnstert.2018.05.004.
An international consortium of polycystic ovary syndrome professional societies and organizations issued new evidence-based recommendations and…
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Pet hamster in the home during pregnancy may contribute to type 1 diabetes risk in offspring

Faresjö AO, et al. Pediatr Diabetes. 2018;doi:10.1111/pedi.12721.
Mothers who reported keeping a pet hamster in the home during pregnancy were more likely to have offspring that developed type 1 diabetes in…
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