EXPERT SUMMARIES of the top 30 journals in endocrinology
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Depression, severe hypoglycemia share bidirectional association in type 1 diabetes

Gilsanz P, et al. Diabetes Care. 2017;doi:10.2337/dc17-1566.
Middle-aged patients with type 1 diabetes diagnosed with depression are at least twice as likely to experience a severe hypoglycemic or hyperglycemic…
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Chinese visceral adiposity index useful marker for cardiometabolic risk in adult GH deficiency

Xie X, et al. Endocr Pract. 2017;doi:10.4158/EP-2017-0007.
The Chinese visceral adiposity index may be used as a biomarker for cardiometabolic risk among adults with growth hormone deficiency, and can also
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Fracture rate similar with DPP-IV inhibitors, sulfonylureas

Gamble JM, et al. Diabetes Res Clin Pract. 2017;doi:10.1016/j.diabres.2017.12.008.
The risk for incident fractures in adults with type 2 diabetes who recently began antidiabetic medication did not differ between those using DPP-IV…
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Calcium, vitamin D supplementation fail to reduce fracture risk

Zhao JG, et al. JAMA. 2017;doi:10.1001/jama.2017.19344.
Supplementation with calcium, vitamin D or a combination of the two was not associated with a lower incidence of hip, nonvertebral, vertebral or…
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Short-term corticosteroids increase risk for adverse events in diabetes

Rogers MAM, et al. J Diabetes. 2017;doi:10.1111/1753-0407.12631.
Adults with diabetes taking short-term oral corticosteroids experienced an increase in the risk for adverse events, though the risk was low and often…
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GH during uterine preparation increases live births after repeated implantation failure

Altmäe S, et al. J Endocr Soc. 2017;doi:10.1210/js.2017-00359.
Infertile women undergoing in vitro fertilization who experienced repeated implantation failure were more likely to have a successful pregnancy when…
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All-cause mortality risk doubles for adults with type 2 diabetes

Rockl S, et al. BMJ Open Diabetes Res Care. 2017;doi:10.1136/bmjdrc-2017-000451.
German adults with type 2 diabetes are twice as likely to die of any cause vs. those without the disease, with the excess risk at least as high for…
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Work stress tied to type 2 diabetes risk

Lian Y, et al. Diabetes Care. 2017;doi:10.2337/dc17-0749.
Chinese adults are at elevated risk for type 2 diabetes when their work stress is increased and their coping resources are decreased, according to…
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Childhood, testicular cancers increase risk for hypogonadism

Isaksson S, et al. Clin Endocrinol. 2017;doi:10.1111/cen.13534.
Men who are survivors of childhood cancer or testicular cancer are at markedly increased risk for developing hypogonadism vs. men in the overall…
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T Trials: Testosterone associated with reductions in cholesterol, insulin

Mohler ER 3rd, at al. J Clin Endocrinol Metab. 2017;doi:10.1210/jc.2017-02243.
Older men with low testosterone randomly assigned to testosterone gel for 1 year saw modest decreases in cholesterol and insulin levels compared with…
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First thyroid data: Age-, sex-dependent differences for cysts, nodules in Fukushima children

Shimura H, et al. J Clin Endocrinol Metab. 2017;doi:10.1210/jc.2017-01603.
Researchers analyzing the first round of thyroid survey data after the 2011 Fukushima Daiichi nuclear accident observed both age- and sex-dependent…
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Mild thyroid dysfunction may lead to unexplained infertility

Jokar TO, et al. J Clin Endocrinol Metab. 2017;doi:10.1210/jc.2017-02120.
Women with unexplained infertility are nearly twice as likely to have high-normal thyroid-stimulating hormone levels compared with women with a…
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Type 2 diabetes risk equations most predictive for middle-aged patients

Alva ML, et al. BMJ Open Diab Res Care. 2017;doi:10.1136/bmjdrc-2017-000447.
Risk equations are more accurate for predicting type 2 diabetes in middle-aged patients than for younger or older groups, researchers found.
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Subcutaneous exenatide delivery lowers HbA1c in adults with type 2 diabetes

Rosenstock J, et al. Diabetes Care. 2017;doi:10.2337/dc17-1306.
The GLP-1 receptor agonist exenatide delivered subcutaneously through an osmotic mini-pump significantly reduced HbA1c and weight compared with…
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HbA1c predicts type 2 diabetes in black, white patients

Leong A, et al. Diabetes Care. 2017;doi:10.2337/dc17-0607.
HbA1c is a useful tool for assessing type 2 diabetes risk in both white and black patients, according to findings recently published in Diabetes

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