EXPERT SUMMARIES of the top 30 journals in endocrinology
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First trimester thyroid hormone levels linked to adverse neonatal outcomes

Hernández M, et al. Clin Endocrinol. 2018;doi:10.1111/cen.13575.
Pregnant women with first trimester thyroid-stimulating hormone levels of 2.5 mIU/L to 5 mIU/L had increased risks for perinatal loss, miscarriage…
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DHEA supplementation may improve pregnancy rates in advanced reproductive age women

Gibson DA, et al. Fert Ster. 2018;doi:10.1016/j.fertnstert.2017.12.024.
In women of advanced reproductive age, supplementation with dehydroepiandrosterone may improve chances for achieving pregnancy, according to findings…
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Low bone density accompanies congenital adrenal hyperplasia

Halper A, et al. Clin Endocrinol. 2018;doi:10.1111/cen.13580.
Children with congenital adrenal hyperplasia tend to have lower bone mineral density compared with healthy children, but body composition is similar…
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Despite benefits, intermittent fasting increases risk for hypoglycemia in type 2 diabetes

Corley BT, et al. Diabet Med. 2018;doi:10.1111/dme.13595.
Intermittent fasting increased hypoglycemia among patients with type 2 diabetes who were treated with hypoglycemic medications, according to the
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Earlier type 2 diabetes diagnosis predicts risk for premature CV death

Huo L, et al. Diabetologia. 2018;doi:10.1007/s00125-018-4544-z.
An earlier diagnosis of type 2 diabetes, and therefore a longer duration of disease, is associated with increased risk for early all-cause death and…
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Drinking water linked to high type 1 diabetes rate in Canadian province

Chafe R, et al. BMJ Open Diabetes Res Care. 2018;doi:10.1136/bmjdrc-2017-000466.
Higher concentrations of arsenic and fluoride in the public drinking water supply in Newfoundland and Labrador may be associated with the high…
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Trans fatty acid concentration independently linked to diabetes in US adults

Liu B, et al. J Diabetes. 2018;doi:10.1111/jdb.12652.
U.S. adults with a diet high in trans fatty acids are more than twice as likely to develop type 2 diabetes than adults with a diet low in trans fatty…
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‘Mutual attraction’ hypothesis does not explain assortative mating in obesity

Wang G, et al. Obesity. 2018;doi:10.1002/oby.22092.
The idea that people with obesity may find other people with obesity physically attractive, also known as the “mutual attraction”…
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ACTIVE: Abaloparatide increases BMD in oldest women subgroup

McClung MR, et al. Menopause. 2018;doi:10.1097/GME.0000000000001080.
In women aged at least 80 years with osteoporosis, bone mineral density at the total hip, femoral neck and lumbar spine increased during 18 months…
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Cholesterol ratio may predict type 2 diabetes risk

Zhang N, et al. J Diabetes. 2018;doi:10.1111/jdb.12650.
In adults aged at least 40 years, the non-HDL cholesterol/HDL cholesterol ratio is an independent risk factor for developing type 2 diabetes…
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DXA imaging may inform atherosclerotic vascular disease risk in older women

Lewis JR, et al. J Bone Miner Res. 2018;doi:10.1002/jbmr.3405.
Abdominal aortic calcification scores assessed using densitometric lateral spine images at the time of bone mineral density testing may identify…
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Xanthine oxidase activity associated with type 2 diabetes risk

Li X, et al. Diabetes Care. 2018;doi:10.2337/dc17-1434.
In both men and women, higher levels of serum xanthine oxidase activity were linked with an increased risk for type 2 diabetes, according to findings…
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Weight loss similar with healthy low-fat, low-carbohydrate diets

Gardner CD, et al. JAMA. 2018;doi:10.1001/jama.2018.0245.
Weight loss over 12 months was substantially the same between adults assigned to a healthy low-fat diet or a healthy low-carbohydrate diet, according…
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Greater CV benefit with canagliflozin vs. other diabetes drugs

Patorno E, et al. BMJ. 2018;doi:10.1136/bmj.k119.
Adults with type 2 diabetes beginning treatment with canagliflozin may have a lower risk for hospital admissions for heart failure, acute myocardial…
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Exercise can benefit metabolic health in obesity

Do K, et al. BMC Obesity. 2018;doi:10.1186/s40608-018-0183-7.
Adults with mild to severe obesity can obtain metabolic health benefits with physical activity and healthy fitness behaviors while remaining obese…

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