EXPERT SUMMARIES of the top 30 journals in endocrinology
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Greater sedentary time associated with metabolic syndrome despite physical activity, cardiorespiratory fitness

van der Velde JHPM, et al. Diabetologia. 2018;doi:10.1007/s00125-018-4719-7.
Cardiorespiratory fitness, higher intensity physical activity and sedentary time each affect metabolic health independently and in combination…
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Prenatal drug exposure may influence stress response, obesity risk in teen girls

Armstrong B, et al. Pediatr Obes. 2018;doi:10.1111/ijpo.12430.
Increased cortisol reactivity may play a mechanistic role in predicting weight gain among adolescent girls, suggesting teens exposed to prenatal drug…
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Hepatitis C triples diabetes risk following kidney transplantation

Liang, J, et al. J Diabetes. 2018;
Risk for developing diabetes after undergoing kidney transplantation increased more than threefold for adults with presurgical hepatitis C infection…
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BPA exposure may alter glucose-stimulated insulin response

Stahlhut RW, et al. J Endocr Soc. 2018;doi:10.1210/js.2018-00151.
Exposure to bisphenol A, or BPA, at a dose deemed safe by U.S. regulatory agencies may change human glucose-stimulated insulin response, according to…
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Thyroid cancer on the rise among young adults in Denmark

Schmidt Jensen J, et al. Thyroid. 2018;doi:10.1089/thy.2018.0067.
The thyroid cancer rate has remained steady since 1980 among Danish children and adolescents, but diagnoses among patients aged 18 to 24 years have…
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Liver enzymes predict type 2 diabetes

Kaneko K, et al. J Diabetes Investig. 2018;doi:10.1111/jdi.12930.
The development of type 2 diabetes among middle-aged Japanese men is associated with parallel increases in levels of the liver enzymes alanine…
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Neonatal TSH levels suggest emerging iodine deficiency in Northern Ireland

Mullan K, et al. Clin Endocrinol. 2018;doi:10.1111/cen.13849.
Researchers have observed an increasing prevalence of neonatal thyroid-stimulating hormone levels greater than 2 mIU/L in Northern Ireland…
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Heart failure increases hospitalization risk for adults with hypothyroidism

Ro K, et al. Thyroid. 2018;doi:10.1089/thy.2017.0362.
Among adults with hypothyroidism, those with congestive heart failure are more likely and those without are less likely to be hospitalized compared…
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Adrenal vein sampling may expose patients with primary aldosteronism to excess radiation

Fuss CT, et al. Eur J Endocrinol. 2018;doi:10.1530/EJE-18-0328.
Patients with primary aldosteronism undergoing adrenal vein sampling to diagnose disease subtype may be exposed to “fairly high” values…
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Vitamin D deficiency increases risk for metabolic syndrome in Chinese youths

Fu J, et al. Clin Nutr. 2018;doi:10.1016/j.clnu.2018.08.039.
Adolescents and young adults with vitamin D deficiency are nearly 2.5 times more likely to have metabolic syndrome vs. those without vitamin D…
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Use of medications associated with rising osteoporosis risk

Skjødt MK, et al. Bone. 2018;doi:10.1016/j.bone.2018.08.019.
The use of medications associated with the development of osteoporosis has steadily increased across Denmark in the past 16 years, particularly by…
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CDC: 14% of US adults have diabetes, many unaware of disease status

Mendola ND, et al. NCHS Data Brief. 2018;319:1-8.
The prevalence of diabetes among adults in the United States rose to 14% between 2013 and 2016, with nearly 31% of those with diabetes unaware they…
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Poor insulin sensitivity can slow information processing, reaction time

Niemiro GM, et al. Obesity. 2018;doi;10.1002/oby.22276.
Cognitive performance in adults with obesity and overweight was negatively affected by poor glucose tolerance and increased visceral fat, according…
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Case management increases bisphosphonate treatment uptake after fragility fracture

Majumdar SR, et al. J Bone Miner Res. 2018;doi:10.1002/jbmr.3557.
Adults who sustained an upper-extremity fragility fracture were more likely to initiate bisphosphonate treatment if participating in a fracture…
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Early signs of fatty liver, subclinical heart disease found in children with metabolically healthy obesity

Di Bonito P, et al. Nutr Metab Cardiovasc Dis. 2018;doi:10.1016/j.numecd.2018.08.007.
Despite a lack of conventional cardiometabolic risk factors, children with so-called metabolically healthy obesity have a higher prevalence of…
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