EXPERT SUMMARIES of the top 30 journals in endocrinology
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Weekly classes improve outcomes of vegan, portion-controlled diets in diabetes management

Barnard ND, et al. J Acad Nutr Diet. 2018;doi:10.1016/j.jand.2017.11.017.
Adults with type 2 diabetes assigned to low-fat vegan or portion-controlled diets, combined with weekly nutrition classes, experienced weight loss…
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Nasal glucagon safe, effective in treating hypoglycemic events in children at home, school

Deeb LC, et al. Pediatr Diabetes. 2018;doi:10.1111/pedi.12668.
Children with type 1 diabetes who experienced a moderate hypoglycemic event returned to euglycemic status within 30 minutes of receiving nasal…
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Childhood obesity project identifies successful strategies in 4 US communities

Kauh TJ, et al. Child Obes. 2018;doi:10.1089/chi.2018.0018.
Researchers from a collaborative team studying successful antiobesity strategies identified four U.S. communities implementing programs and policies…
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Novel neuropeptide may hold clues to obesity, diabetes risk

Lin CY, et al. J Endocr Soc. 2018;doi:10.1210/js.2018-00020.
Levels of circulating spexin, a newly identified neuropeptide, decrease with age and may predict risk for obesity and diabetes, according to findings…
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Specialized diabetes teams reduce hospital readmissions, costs

Bansal V, et al. BMJ Open Diabetes Res Care. 2018;doi:10.1136/bmjdrc-2017-000460.
Hospitalized patients with diabetes managed by a specialized diabetes team were less likely to be readmitted within 30 days vs. patients managed by a…
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Nutritional status changes fracture risk in hypothalamic amenorrhea

Kandemir N, et al. J Clin Endocrinol Metab. 2018;doi:10.1210/jc.2018-00338.
Adolescent girls and young women with hypothalamic amenorrhea have differing fracture risks depending on whether the condition was brought on by…
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Denosumab more effective than risedronate in glucocorticoid-induced osteoporosis

Saag KG, et al. Lancet Diabetes Endocrinol. 2018;doi:10.1016/s2213-8587(18)30075-5.
Adults with a history of glucocorticoid-induced osteoporosis assigned to therapy with the monoclonal antibody denosumab experienced a greater…
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Eplerenone may improve inflammatory markers, but not insulin sensitivity in HIV

Srinivasa S, et al. J Clin Endocrinol Metab. 2018;doi:10.1210/jc.2018-00330.
Insulin sensitivity and HbA1c were not substantially affected by treatment with eplerenone compared with placebo in adults with HIV; however, those…
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Mental health diagnoses more common among PCOS women, offspring

Berni TR, et al. J Clin Endocrinol Metab. 2018; doi10.1210/jc.2017-02667.
Women with polycystic ovary syndrome are more likely to be diagnosed with mental health conditions, including depression, anxiety and bipolar…
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Diabetes increases mortality rate in overt heart failure

Rørth R, et al. Diabetes Care. 2018;doi:10.2337/dc17-2583.
Among adults with asymptomatic left ventricular systolic dysfunction who developed heart failure, those with diabetes had increased risks for heart…
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Gestational diabetes increases obstructive sleep apnea risk in offspring

Zamstein O, et al. Diabetes Res Clin Pract. 2018;doi:10.1016/j.diabres.2018.03.050.
Children of mothers with gestational diabetes had a greater risk for obstructive sleep apnea vs. children of healthy mothers, whereas risks for…
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Diabetes, hypertension persist despite successful acromegaly treatment

Gonzalez B, et al. J Clin Endocrinol Metab. 2018;doi:10.1210/jc.2018-00325.
Diabetes and hypertension are common among Mexico residents with acromegaly despite successful medical or surgical treatment of the disease…
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Diabetic ketoacidosis risk lower in children with ongoing provider relationship

Guttmann A. CMAJ. 2018;doi:10.1503/cmaj.180220.
Nakhla M, et al. CMAJ. 2018;doi:10.1503/cmaj.170676.
Canadian children and adolescents with newly diagnosed type 1 diabetes treated by a usual care provider were less likely to have diabetic…
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Higher carotenoid consumption associated with reduced hip fracture risk

Cao WT, et al. Bone. 2018;doi:10.1016/j.bone.2018.03.023.
Chinese adults who consume greater levels of carotenoids, including foods rich in beta-carotene, lycopene and lutein, are less likely to experience…
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Intensive lifestyle weight-loss program reduces physical disability later in life

Gregg EW, et al. Diabetes Care. 2018;doi:10.2337/dc17-2110.
Adults with type 2 diabetes and overweight or obesity assigned to an intensive lifestyle intervention for weight loss were less likely to experience…
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