EXPERT SUMMARIES of the top 30 journals in endocrinology
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Maternal hypothyroidism may influence risk for neurodevelopmental disorders in offspring

Thompson W, et al. Clin Endocrinol. 2018;doi:10.1111/cen.13550.
Children born to women with subclinical hypothyroidism and hypothyroxinemia during pregnancy are more likely to have an intellectual disability than…
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Teriparatide reduces fracture risk in women with severe osteoporosis

Geusens P, et al. J Bone Miner Res. 2018;doi:10.1002/jbmr.3384.
Postmenopausal women with severe osteoporosis may have a lower risk for new vertebral fractures when treated with the anabolic agent teriparatide…
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Graves’ orbitopathy risk linked to cholesterol levels

Sabini E, et al. Thyroid. 2018;doi:10.1089/thy.2017.0430.
In adults with Graves’ disease, the risk for Graves’ orbitopathy may be associated with increased levels of total and LDL cholesterol…
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PCOS-like characteristics do not raise diabetes risk in women with overweight

Kim C, et al. J Clin Endocrinol Metab. 2017;doi:10.1210/jc.2017-01829.
Irregular menses and elevated androgen concentrations did not increase risk for coronary artery calcification or diabetes among women with glucose…
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All-cause, CVD mortality tied to 25-(OH)D concentrations

Degerud E, et al. J Clin Endocrinol Metab. 2018;doi:10.1210/jc.2017-02328.
Adults with suspected stable angina pectoris who have serum 25-hydroxyvitamin D levels less than 42.5 nmol/L or more than 100 nmol/L have an…
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US diabetes detection rates remain low for some populations

Geiss LS, et al. BMJ Open Diabetes Res Care. 2018;doi:10.1136/bmjdrc-2017-000487.
The overall detection rate of undiagnosed type 2 diabetes in the United States did not increase between 1999 and 2014, despite small improvements…
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Early radioactive iodine initiation may improve treatment response after thyroidectomy

Li H, et al. Clin Endocrinol. 2018;doi:10.1111/cen.13551.
Adults with differentiated thyroid cancer who underwent thyroidectomy and started radioiodine therapy 3 or more months after surgery may have an…
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Real-time CGM reimbursement improves glycemic control in type 1 diabetes

Charleer S, et al. J Clin Endocrinol Metab. 2018;doi:10.1210/jc.2017-02498.
Real-time continuous glucose monitoring improves HbA1c, reduces hospitalizations for severe hypoglycemia or ketoacidosis and elevates quality of life…
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Long-term adherence to LDL targets lacking in type 1 diabetes

Swasey KK, et al. J Diabetes Investig. 2018;doi:10.1016/j.jdiacomp.2018.01.003.
The percentage of adults with type 1 diabetes who met LDL cholesterol recommendations set by the American Diabetes Association has steadily declined…
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Sugars represent more than one-quarter of children’s calories

Welsh JA, et al. Pediatr Obes. 2018;doi:10.1111/ijpo.12264.
More than 25% of the calories children consume comes from sugars, including nearly 15% added sugars, leading to varying effects on body weight…
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Late-night salivary cortisol often fluctuates widely in Cushing’s disease

Sandouk Z, et al. J Clin Endocrinol Metab. 2018;doi:10.1210/jc.2017-02020.
Among patients with new, persistent or recurrent Cushing’s disease, researchers observed cortisol levels that fluctuated widely over 6 months…
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Newly identified gene mutation likely behind diabetes, insulin-producing tumors

Iacovazzo D, et al. Proc Natl Acad Sci. 2018;doi:10.1073/pnas.1712262115.
Researchers have identified a missense mutation in a gene responsible for the regulation of insulin secretion that is likely associated with two…
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Nearly 25% of patients maintain diabetes control 5 years after obesity surgery

Ikramuddin S, et al. JAMA. 2018;doi:10.1001/jama.2017.20813.
Among adults prescribed intensive lifestyle and medical management for obesity, those who also underwent Roux-en-Y gastric bypass surgery were more…
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Lactation duration tied to diabetes risk

Gunderson EP, et al. JAMA Intern Med. 2018;doi:10.1001/jamainternmed.2017.7978.
Women who breast-feed may have a lower risk for diabetes compared with those who never breast-fed, with the lowest risk among those with a lactation…
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Despite benefits, risks remain after bariatric surgery

Jakobsen GS, et al. JAMA. 2018;doi:10.1001/jama.2017.21055.
Patients with obesity who underwent bariatric surgery had increased risks for depression, anxiety, sleep disorders and treatment with opioid drugs…

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