EXPERT SUMMARIES of the top 30 journals in endocrinology
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SGLT2 inhibitors demonstrate real-world CV benefit in type 2 diabetes

Udell JA, et al. Circulation. 2017;doi:10.1161/CIRCULATIONAHA.117.031227.
Adults with type 2 diabetes and established cardiovascular disease treated with an SGLT2 inhibitor have lower risks for all-cause mortality…
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Prepregnancy BMI, gestational weight gain influence C-reactive protein levels in breast milk

Whitaker KM, et al. Obesity. 2017;doi:10.1002/oby.22025.
Women with a high prepregnancy BMI or those who gain excessive weight during pregnancy are more likely to have higher levels of the inflammatory…
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Beyond 25-(OH)D, vitamin D metabolite ratio may better predict hip fracture risk

Ginsberg C, et al. Bone. 2017;doi:10.1016/j.bone.2017.11.011.
Among older adults, a lower 24,25-dihydroxyvitamin D to 25-hydroxyvitamin D ratio, also known as the vitamin D metabolic ratio, is a stronger…
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More than half of US children destined for obesity in adulthood

Ward ZJ, et al. N Engl J Med. 2017;doi:10.1056/NEJMoa1703860.
More than half of U.S. children will have obesity by age 35 years if current trends continue, according to results gathered from a simulation model…
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Competitive bidding program limits diabetes supply access

Puckrein GA, et al. Diabetes Care. 2017;doi:10.2337/dc17-0960.
Medicare beneficiaries with diabetes experienced disruptions in access to diabetes testing supplies after the initial rollout of the CMS competitive…
In the Journals PlusPerspective

Real-time CGM improves hypoglycemic awareness

Rickels MR, et al. J Clin Endocrinol Metab. 2017;doi:10.1210/jc.2017-01516.
Adults with long-standing type 1 diabetes may increase awareness of hypoglycemia and reduce severity of hypoglycemic events by using real-time…
In the Journals PlusPerspective

Diabetes, high BMI cause nearly 6% of cancers worldwide

Pearson-Stuttard J, et al. Lancet Diabetes Endocrinol. 2017;doi:10.1016/s2213-8587(17)30366-2.
Approximately 5.6% of all incident cancers in 2012 were attributable to the combined effects of diabetes and high BMI as independent risk factors…
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DHA supplementation reduces placental inflammation in women with obesity

Lager S, et al. J Clin Endocrinol Metab. 2017;doi:10.1210/jc.2017-01384.
In pregnant women with obesity, docosahexaenoic acid, or DHA, supplementation decreased placental inflammation and could mitigate the negative
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Survey: More individualized treatment needed in HT for disorders of sex development

Nordenstrom A, et al. Clin Endocrinol. 2017;doi:10.1111/cen.13518.
Patients with various disorders of sex development generally report being satisfied with hormone therapy, but survey responses regarding adverse…
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Oral device reduces food intake, promotes weight loss in obesity

Ryan DH, et al. Obes Sci Pract. 2017;doi:10.1002/osp4.139.
Adults with overweight or obesity who used a removable, oral device while eating meals and snacks saw a mean excess weight loss of nearly 19% after…
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Healthy diet associated with meeting metabolic targets

Sarmento RA, et al. J Endocr Soc. 2017;doi:10.1210/js.2017-00349.
Brazilian patients with type 2 diabetes who reported consuming a diet high in whole carbohydrates, dairy, white meat and fish were more likely to…
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Bariatric surgery associated with reduced psoriasis risk

Maglio C, et al. Obesity. 2017;doi:10.1002/oby.21955.
Adults with obesity who underwent bariatric surgery were less likely to develop psoriasis vs. those who received usual care, according to findings…
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Long-term GH increases height, not growth potential in juvenile arthritis

Simon D, et al. J Clin Endocrinol Metab. 2017;doi:10.1210/jc.2017-01455.
Researchers in France reported that although long-term treatment with growth hormone improved growth in patients with juvenile idiopathic arthritis
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Short-term sitagliptin therapy preserves beta-cell function in women with PCOS, obesity

Ferjan S, et al. Endocr Pract. 2017;doi:10.4158/EP-2017-0027.
Among women with polycystic ovary syndrome and obesity participating in a lifestyle intervention, those who were assigned the DPP-IV inhibitor…
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Joint endocrinologist-nephrologist clinic reduced diabetic kidney disease progression

Low S, et al. J Diabetes. 2017;doi:10.1111/jdb.12626.
Patients with type 2 diabetes and stage 3 or 4 chronic kidney disease who attended a joint endocrinologist-nephrologist diabetic kidney disease…
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