EXPERT SUMMARIES of the top 30 journals in endocrinology
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Denosumab more effective than risedronate in glucocorticoid-induced osteoporosis

Saag KG, et al. Lancet Diabetes Endocrinol. 2018;doi:10.1016/s2213-8587(18)30075-5.
Adults with a history of glucocorticoid-induced osteoporosis assigned to therapy with the monoclonal antibody denosumab experienced a greater…
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Eplerenone may improve inflammatory markers, but not insulin sensitivity in HIV

Srinivasa S, et al. J Clin Endocrinol Metab. 2018;doi:10.1210/jc.2018-00330.
Insulin sensitivity and HbA1c were not substantially affected by treatment with eplerenone compared with placebo in adults with HIV; however, those…
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Mental health diagnoses more common among PCOS women, offspring

Berni TR, et al. J Clin Endocrinol Metab. 2018; doi10.1210/jc.2017-02667.
Women with polycystic ovary syndrome are more likely to be diagnosed with mental health conditions, including depression, anxiety and bipolar…
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Diabetes increases mortality rate in overt heart failure

Rørth R, et al. Diabetes Care. 2018;doi:10.2337/dc17-2583.
Among adults with asymptomatic left ventricular systolic dysfunction who developed heart failure, those with diabetes had increased risks for heart…
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Gestational diabetes increases obstructive sleep apnea risk in offspring

Zamstein O, et al. Diabetes Res Clin Pract. 2018;doi:10.1016/j.diabres.2018.03.050.
Children of mothers with gestational diabetes had a greater risk for obstructive sleep apnea vs. children of healthy mothers, whereas risks for…
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Diabetes, hypertension persist despite successful acromegaly treatment

Gonzalez B, et al. J Clin Endocrinol Metab. 2018;doi:10.1210/jc.2018-00325.
Diabetes and hypertension are common among Mexico residents with acromegaly despite successful medical or surgical treatment of the disease…
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Diabetic ketoacidosis risk lower in children with ongoing provider relationship

Guttmann A. CMAJ. 2018;doi:10.1503/cmaj.180220.
Nakhla M, et al. CMAJ. 2018;doi:10.1503/cmaj.170676.
Canadian children and adolescents with newly diagnosed type 1 diabetes treated by a usual care provider were less likely to have diabetic…
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Higher carotenoid consumption associated with reduced hip fracture risk

Cao WT, et al. Bone. 2018;doi:10.1016/j.bone.2018.03.023.
Chinese adults who consume greater levels of carotenoids, including foods rich in beta-carotene, lycopene and lutein, are less likely to experience…
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Intensive lifestyle weight-loss program reduces physical disability later in life

Gregg EW, et al. Diabetes Care. 2018;doi:10.2337/dc17-2110.
Adults with type 2 diabetes and overweight or obesity assigned to an intensive lifestyle intervention for weight loss were less likely to experience…
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Health care professionals lack knowledge of evidence-based obesity treatment

Kushner R. Obesity. 2018;doi:10.1002/oby.22161.
Turner M, et al. Obesity. 2018;doi:10.1002/oby.22142.
Health care providers have a limited understanding of evidence-based recommendations to address obesity, according to findings published in…
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CV, cerebrovascular risks increase after noncardiac surgery in adults with diabetes

Newman JD, et al. Diabetes Care. 2018;doi:10.2337/dc17-2046.
Adults with diabetes have a higher risk for major cardiovascular and cerebrovascular events, including mortality and acute myocardial infarction…
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In MEN1, fear of disease recurrence lowers quality of life

van Leeuwaarde RS, et al. J Clin Endocrinol Metab. 2018;doi:10.1210/jc.2018-00259.
Among adults with multiple endocrine neoplasia type 1, or MEN1, a high fear of disease occurrence is associated with a lower health-related quality…
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Epilepsy tied to severe hypoglycemia in type 2 diabetes

Lu C, et al. Diabetes Res Clin Pract. 2018;doi:10.1016/j.diabres.2018.03.020.
Adults with type 2 diabetes have an increased risk for epilepsy, especially in the presence of severe hypoglycemia, compared with adults without type…
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Dining out linked to increased exposure to endocrine-disrupting chemicals in foods

Varshavsky JR, et al. Environ Int. 2018;doi:10.1016/j.envint.2018.02.029.
U.S. children and adults who consume food from sources away from home are more likely to have higher measurements of endocrine-disrupting phthalates…
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Free T3, LDL cholesterol inversely associated in euthyroid women

Guarnizo-Poma M, et al. Diabetes Metab Syndr. 2018;doi:10.1016/j.dsx.2018.03.023.
Among a group of euthyroid women, researchers found inversely related levels of free triiodothyronine and LDL cholesterol. Vicente A
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