EXPERT SUMMARIES of the top 30 journals in endocrinology
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Thyroid cancer on the rise among young adults in Denmark

Schmidt Jensen J, et al. Thyroid. 2018;doi:10.1089/thy.2018.0067.
The thyroid cancer rate has remained steady since 1980 among Danish children and adolescents, but diagnoses among patients aged 18 to 24 years have…
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Liver enzymes predict type 2 diabetes

Kaneko K, et al. J Diabetes Investig. 2018;doi:10.1111/jdi.12930.
The development of type 2 diabetes among middle-aged Japanese men is associated with parallel increases in levels of the liver enzymes alanine…
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Neonatal TSH levels suggest emerging iodine deficiency in Northern Ireland

Mullan K, et al. Clin Endocrinol. 2018;doi:10.1111/cen.13849.
Researchers have observed an increasing prevalence of neonatal thyroid-stimulating hormone levels greater than 2 mIU/L in Northern Ireland…
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Heart failure increases hospitalization risk for adults with hypothyroidism

Ro K, et al. Thyroid. 2018;doi:10.1089/thy.2017.0362.
Among adults with hypothyroidism, those with congestive heart failure are more likely and those without are less likely to be hospitalized compared…
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Adrenal vein sampling may expose patients with primary aldosteronism to excess radiation

Fuss CT, et al. Eur J Endocrinol. 2018;doi:10.1530/EJE-18-0328.
Patients with primary aldosteronism undergoing adrenal vein sampling to diagnose disease subtype may be exposed to “fairly high” values…
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Vitamin D deficiency increases risk for metabolic syndrome in Chinese youths

Fu J, et al. Clin Nutr. 2018;doi:10.1016/j.clnu.2018.08.039.
Adolescents and young adults with vitamin D deficiency are nearly 2.5 times more likely to have metabolic syndrome vs. those without vitamin D…
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Use of medications associated with rising osteoporosis risk

Skjødt MK, et al. Bone. 2018;doi:10.1016/j.bone.2018.08.019.
The use of medications associated with the development of osteoporosis has steadily increased across Denmark in the past 16 years, particularly by…
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CDC: 14% of US adults have diabetes, many unaware of disease status

Mendola ND, et al. NCHS Data Brief. 2018;319:1-8.
The prevalence of diabetes among adults in the United States rose to 14% between 2013 and 2016, with nearly 31% of those with diabetes unaware they…
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Poor insulin sensitivity can slow information processing, reaction time

Niemiro GM, et al. Obesity. 2018;doi;10.1002/oby.22276.
Cognitive performance in adults with obesity and overweight was negatively affected by poor glucose tolerance and increased visceral fat, according…
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Case management increases bisphosphonate treatment uptake after fragility fracture

Majumdar SR, et al. J Bone Miner Res. 2018;doi:10.1002/jbmr.3557.
Adults who sustained an upper-extremity fragility fracture were more likely to initiate bisphosphonate treatment if participating in a fracture…
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Early signs of fatty liver, subclinical heart disease found in children with metabolically healthy obesity

Di Bonito P, et al. Nutr Metab Cardiovasc Dis. 2018;doi:10.1016/j.numecd.2018.08.007.
Despite a lack of conventional cardiometabolic risk factors, children with so-called metabolically healthy obesity have a higher prevalence of…
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Melatonin may play role in diabetes risk in men

Obayashi K, et al. Clin Endocrinol. 2018;doi:10.1111/cen.13842.
A higher endogenous melatonin level in older Japanese men may be associated with decreased risk for developing type 2 diabetes, according to findings…
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Metformin ineffective for long-term metabolic improvements in teen obesity

Lentferink YE, et al. Nutr Diabetes. 2018;doi:10.1038/s41387-018-0057-6.
Adolescents with obesity assigned to long-term metformin therapy experienced initial improvements in BMI and insulin resistance that were not…
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USPSTF endorses behavioral weight-loss intervention, offers less support for medications

September 18, 2018
In an update to its 2012 recommendation, the U.S. Preventive Services Task Force continued to recommend that physicians not only screen for…
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Oral clonidine effectively, safely diagnoses pediatric GH deficiency

Ibba A, et al. Clin Endocrinol. 2018;doi:10.1111/cen.13845.
Among pubertal and prepubertal children with suspected growth hormone deficiency, the adrenergic agonist clonidine can accurately and safely diagnose…
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