EXPERT SUMMARIES of the top 30 journals in endocrinology
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Long-term weight loss, diabetes remission maintained after RYGB

Courcoulas AP, et al. JAMA Surg, 2017;doi:10.1001/jamasurg.2017.5025.
Higa KD, et al. JAMA Surg. 2017;doi:10.1001/jamasurg.2017.5010.
Adults with obesity who underwent Roux-en-Y gastric bypass were likely to maintain much of their weight loss with variable weight fluctuations long…
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Women with PCOS report ‘sense of inevitability’ regarding weight gain, adverse outcomes

Lin AW, et al. Hum Reprod. 2017;doi:10.1093/humrep/dex351.
Women with polycystic ovary syndrome were more likely to report they had concerns regarding long-term health risks, including cardiovascular disease…
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Type 2 diabetes remission possible with diet, weight loss in primary care

Lean MEJ, et al. Lancet. 2017;doi:10.1016/S0140-6736(17)33102-1.
Uusitupa M. Lancet. 2017;doi:10.1016/S0140-6736(17)33100-8.
An intensive weight management program delivered in the primary care setting was effective for diabetes remission and weight loss in adults with type…
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Probiotic supplementation aids wound healing in diabetic foot ulcer

Mohseni S, et al. Diabetes Metab Res Rev. 2017;doi:10.1002/dmrr.2970.
Patients with a diabetic foot ulcer who received probiotic supplementation for 12 weeks experienced faster wound healing coupled with an improved…
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Early, sustained glucose control lowers CVD risk in newly diagnosed type 2 diabetes

Alatorre CI, et al. Curr Med Res Opin. 2017;doi:10.1080/03007995.2017.1396969.
Patients with type 2 diabetes who achieve early and sustained HbA1c control between 6.5% and 7% were substantially less likely to experience a…
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Cross-sex HT induces sex-specific changes in android, gynoid regions

Klaver M, et al. Eur J Endocrinol. 2017;doi:10.1530/EJE-17-0496.
Transgender women and men initiating cross-sex hormone therapy experienced anthropomorphic changes over 1 year associated with more feminine and…
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Predictive low-glucose management system reduces hypoglycemia in adolescents with type 1 diabetes

Abraham MB, et al. Diabetes Care. 2017;doi:10.2337/dc17-1604.
Children and adolescents with type 1 diabetes using a predictive low-glucose management system experienced greater reductions in time spent in…
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Older antiretroviral regimens raise diabetes risk in HIV-positive adults

Samad F, et al. BMJ Open Diabetes Res Care. 2017;doi:10.1136/bmjdrc-2017-000457.
HIV-positive adults who initiated older formulations of antiretroviral therapy are more likely to develop type 2 diabetes than patients who initiated…
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Higher testosterone levels may protect against frailty in men

Swiecicka A, et al. J Clin Endocrinol Metab. 2017;doi:10.1210/jc.2017-01172.
Frailty in aging men may be associated with low levels of free testosterone and high levels of sex hormone-binding globulin, follicle-stimulating…
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Across ethnicities, men more likely to develop diabetes

Ferguson LD, et al. Diabet Med. 2017;doi:10.1111/dme.13551.
Across ethnic groups, men are significantly more likely to develop diabetes than women, with the risk persisting after factoring in age and BMI…
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Anti-Müllerian hormone predictive of PCOS

Sathyalapan T, et al. Clin Endocrinol. 2017;doi:10.1111/cen.13517.
Elevated levels of anti-Mullerian hormone were four times more predictive of polycystic ovary syndrome than serum testosterone or free androgen index
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Early HT initiation not linked to stroke risk in postmenopausal women

Carrasquilla GD, et al. PLoS Med. 2017;doi:10.1371/journal.pmed.1002445.
The risk for stroke in postmenopausal women was not increased with hormone therapy —regardless of administration route, type of therapy or…
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Increased diabetes prevalence persists in acromegaly, even after remission

Rochette C, et al. J Endocr Soc. 2017;doi:10.1210/js.2017-00334.
Patients with acromegaly that is controlled through medication or in remission continue to have a higher prevalence of diabetes than the general…
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New consensus report standardizes diabetes outcomes beyond HbA1c

Agiostratidou G, et al. Diabetes Care. 2017;doi:10.2337/dc17-1624.
Stakeholders in the type 1 diabetes community are recommending the use of standardized definitions for several diabetes outcome measurements beyond…
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Link between obesity, mortality weakens as patients age

Wang Z, et al. Obesity. 2017;doi:10.1002/oby.21976.
Associations between obesity and mortality decreased as patients aged, according to findings recently published in Obesity. Researchers wrote that

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