EXPERT SUMMARIES of the top 30 journals in endocrinology
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Low-dose menopausal HT cessation does not affect progression of preclinical atherosclerosis

Miller VM, et al. Menopause. 2018;doi:10.1097/GME.0000000000001167.
Menopausal women who discontinued low doses of hormone therapy did not experience accelerated changes in carotid artery intima-media thickness during…
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In China, regional disparities persist in prevalence of CHD, stroke in type 2 diabetes

Lyu Y, et al. J Clin Endocrinol Metab. 2018;doi:10.1210/jc.2018-00422.
Significant regional differences exist in the prevalence and risks for coronary heart disease and stroke among adults with type 2 diabetes in China…
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Rate of HbA1c increase influences risk for diabetic polyneuropathy

Anderson ST, et al. Diabetes Care. 2018;doi:10.2337/dc18-0392.
Among adults with type 2 diabetes, each 1% increase in HbA1c during 10 years increases the risk for diabetic polyneuropathy by nearly 66%, according
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Insulin resistance does not influence anti-Müllerian hormone levels in PCOS

Sahmay S, et al. Eur J Obstet Gynecol Reprod Biol. 2018;doi:10.1016/j.ejogrb.2018.03.007.
Women with polycystic ovary syndrome had similar anti-Müllerian hormone levels regardless of whether they also had insulin resistance, according…
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Leptin to adiponectin ratio may predict metabolic dysfunction in obesity

Larsen MA, et al. Nutr Metab Cardiovasc Dis. 2018;doi:10.1016/j.numecd.2018.06.020.
The ratio of leptin to adiponectin may be a useful surrogate biomarker for early obesity-related metabolic disorders, such as leptin resistance…
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For transgender youths, delay in cross-sex HT initiation increases risk for smoking

Menino DD, et al. Transgend Health. 2018;doi:10.1089/trgh.2018.0002.
Among transgender adolescents, a longer delay between the recognition of transgender identity and the initiation of cross-sex hormone therapy is…
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Fasting glucose plus physical performance may predict diabetes risk

Zhang W, et al. J Diabetes. 2018;doi:10.1111/1753-0407.12816.
Among older Chinese adults with impaired fasting glucose, elevated glucose level together with reduced muscle strength was associated with glycemic…
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Delay in bottle-feeding may reduce early childhood obesity risk

Ortega-Garcia JA, et al. Child Obes. 2018;doi:10.1089/chi.2017.0335.
Among children whose introduction to bottle-feeding is delayed, the longer duration of breastfeeding may confer protection against obesity at age 6…
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Educational, emotional interventions reduce diabetes distress

Fisher L, et al. Diabetes Care. 2018;doi:10.2337/dc18-0391.
Both educational/behavioral and emotional interventions may aid in reducing diabetes distress among adults with type 1 diabetes, according to a study…
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Early pregnancy iron deficiency may predict hypothyroxinemia in second, third trimester

Teng X, et al. Thyroid. 2018;doi:10.1089/thy.2017.0491.
Pregnant women with iron deficiency in the first trimester are more likely to have lower levels of free thyroxine and an increased risk for…
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‘Normal-weight obesity’ linked to cardiometabolic risk in Chinese adults

Jia A, et al. Nutr Metab Cardiovasc Dis. 2018;doi:10.1016/j.numecd.2018.06.015.
Normal-weight obesity — defined as a high body fat percentage in the setting of normal BMI — is relatively common in China, and the…
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Levothyroxine dose in infancy may predict transient congenital hypothyroidism in children

Saba C, et al. Thyroid. 2018;doi:10.1089/thy.2018.0154.
Infants prescribed a lower dose of levothyroxine therapy for congenital hypothyroidism with a eutopic thyroid gland are more likely to have a…
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Parkinson's disease risk nearly doubles for those with diabetic retinopathy

Eun Lee S, et al. J Clin Endocrinol Metab. 2018;doi:10.1210/jc.2017-02774.
Adults with diabetic retinopathy are nearly twice as likely to develop Parkinson’s disease as those without the condition, according to a study…
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In childhood cancer survivors, GH therapy improves height without secondary tumor risk

Tamhane S, et al. J Clin Endocrinol Metab. 2018;doi:10.1210/jc.2018-01205.
In childhood cancer survivors, treatment with growth hormone was associated with gains in height vs. untreated control patients without increased…
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Renal calcifications associated with disease severity in primary hyperparathyroidism

Ejlsmark-Svensson H, et al. J Clin Endocrinol Metab. 2018;doi:10.1210/jc.2018-00923.
Patients with primary hyperparathyroidism have a high prevalence of renal calcifications that are typically linked to the severity of the disease
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