EXPERT SUMMARIES of the top 30 journals in endocrinology
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'Intensification inertia' potentially hinders HbA1c goal attainment

Pantalone KM, et al. Diabet Med. 2019;doi:10.1111/dme.13900.
Intensifying drug therapies did not help most adults with type 2 diabetes attain HbA1c goals, but the best results were seen with the addition of a…
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HT does not alter vitamin D levels in transgender adults

Chen H, et al. J Clin Endocrinol Metab. 2019;doi:10.1210/jc.2018-02602.
Transgender women experience only small changes in vitamin D-binding protein after 3 months of estradiol therapy, whereas testosterone therapy was…
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Nodular thyroid disease risk increased for adults with acromegaly

Dogansen SC, et al. Pituitary. 2019;doi:10.1007/s11102-018-0923-1.
Adults with acromegaly may be prone to developing nodular thyroid disease and advanced nodule growth, according to findings published in…
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HbA1c promising as predictive measure for cystic fibrosis-related diabetes

Choudhury M, et al. Diabet Med. 2019;doi:10.1111/dme.13912.
Adults with cystic fibrosis and HbA1c levels of 37 mmol/mol or more are at greater risk for dysglycemia and cystic fibrosis-related diabetes than…
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Maternal cortisol to cortisone ratio may predict preeclampsia, fetal growth restriction

Jayasuriya NA, et al. J Clin Endocrinol Metab. 2019;doi:10.1210/jc.2018-02312.
A lower maternal serum cortisol to cortisone ratio, a marker of placental function, precedes the clinical manifestation of preeclampsia and preterm…
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Better knowledge of gadolinium retention risks needed for pituitary tumor MRIs

Nachtigall LB, et al. Pituitary. 2019;doi:10.1007/s11102-018-0924-0.
Pituitary tumor management via ongoing MRIs is recommended by most endocrinologists and pituitary neurosurgeons, but there is a need to improve…
In the Journals PlusPerspective

Carbs before sprinting exercises do not disrupt glycemic management

Soon WHK, et al. Diabet Med. 2019;doi:10.1111/dme.13914.
Glycemic management for young people with type 1 diabetes may not be negatively affected by carbohydrate intake before exercise that includes…
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Metformin may reduce risk for miscarriage, preterm birth in pregnancy with PCOS

Løvvik TS, et al. Lancet Diabetes Endocrinol. 2019;doi:10.1016/s2213-8587(19)30002-6.
Pregnant women with polycystic ovary syndrome assigned to metformin therapy for the duration of pregnancy were less likely to experience a late-term…
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Behavioral therapy 'missing ingredient' for digital health success in diabetes

Klonoff DC. J Diabetes Sci Technol. 2019;doi:10.1177/1932296818820303.
Digital health tools designed to improve disease management for patients with diabetes often have little effect on long-term health outcomes, likely…
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Adjuvant therapy improves odds of TSH-secreting pituitary adenoma remission

Cossu G, et al. Pituitary. 2019;doi:10.1007/s11102-018-0921-3.
Adults with thyroid-stimulating hormone-secreting pituitary adenomas have a greater chance of biochemical remission after undergoing adjuvant…
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Pituitary abnormalities 'underestimated' in adults with autoimmune pancreatitis

Kanie K, et al. Pituitary. 2019;doi:10.1007/s11102-018-00930-y.
Adults with autoimmune pancreatitis may have higher rates of immunoglobulin G4-related hypophysitis than previously thought, according to findings…
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Smartphone camera presents potential alternative for diabetic foot ulcer detection

van Doremalen RFM, et al. Diabetes Res Clin Pract. 2019;doi:10.1016/j.diabres.2019.01.032.
Diabetic foot ulcer can be detected effectively using an infrared camera on a smartphone, even when compared with a high-end infrared camera usually…
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Advanced glycation end product accumulation, insulin resistance share 'two-way' relationship

Uruska A, et al. Diabet Med. 2019;doi:10.1111/dme.13921.
Insulin resistance and the accumulation of advanced glycation end products in the skin have a “two-way” relationship for adults with type…
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Early maternal menarche associated with obesity risk in sons

Hong Y, et al. Clin Endocrinol. 2019;doi:10.1111/cen.13948.
Adolescent boys whose mothers were younger at menarche are at increased risk for obesity vs. sons of mothers with older menarche, according to…
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Consistent vitamin D sufficiency may limit preeclampsia risk

Benachi A, et al. Clin Nutr. 2019;doi:10.1016/j.clnu.2019.02.015.
Preeclampsia risk is lower for women with vitamin D sufficiency in the first and third trimesters of pregnancy compared with women with vitamin D…
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