EXPERT SUMMARIES of the top 30 journals in endocrinology
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GH therapy improves emotional, social quality of life in children with short stature

González Briceño LG, et al. J Clin Endocrinol Metab. 2019;doi:10.1210/jc.2018-02523.
Children with short stature who received 1 year of growth hormone treatment experienced improvements in emotional and social quality-of-life measures…
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Gestational diabetes plus prepregnancy obesity increases risk for higher infant birth weight

Yasuda S, et al. J Diabetes Investig. 2018;doi:10.1111/jdi.12989.
Excessive gestational weight gain and prepregnancy overweight or obesity among Japanese women with gestational diabetes was associated with higher…
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Microneedle contraceptive patch may offer new option for women

Li W, et al. Nat Biomed Eng. 2019; doi:10.6084/m9.figshare.6025748.
In animal models, an experimental, microneedle skin patch provided a therapeutic level of contraceptive hormone for more than 1 month with a single…
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Combining metformin, intensive lifestyle marginally improves glycemic control, body mass

Terada T, et al. Metabolism. 2019;doi:10.1016/j.metabol.2019.01.004.
Metformin therapy has a small effect on glycemic control and changes in body mass when combined with intensive lifestyle interventions in adults with…
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Influence of HbA1c on fracture risk differs in type 1, type 2 diabetes

Vavanikunnel J, et al. J Clin Endocrinol Metab. 2019;doi:10.1210/jc.2018-01879.
Adults with type 1 diabetes and an HbA1c of at least 8% were more likely to sustain a low-trauma fracture in the 4 years after diabetes diagnosis…
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Meal timing may affect cholesterol levels

Chen HJ, et al. Nutr Metab Cardiovasc Dis. 2019;doi:10.1016/j.numecd.2019.01.003.
LDL cholesterol levels can be lowered by eating less at night and shifting late-evening fat intake to earlier in the day, according to findings…
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Interdependence may hinder diabetes self-care in Japanese adults

Mano F, et al. J Diabetes Investig. 2018;doi:10.1111/jdi.12983.
Diabetes self-care in Japanese adults with type 2 diabetes can be negatively affected by interdependent tendencies, according to findings published…
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Gastric bypass surgery leads to improved strength, physical performance

Alba D, et al. J Clin Endocrinol Metab. 2019;doi:10.1210/jc.2018-00952.
Relative muscle strength and physical function improve in adults after Roux-en-Y gastric bypass surgery, according to findings published in The
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CVD risk increases with transition to metabolically unhealthy obesity

Kouvari M, et al. Metabolism. 2019;doi:10.1016/j.metabol.2019.01.003.
Adults who transition from metabolically healthy obesity to metabolically unhealthy obesity are at increased risk for cardiovascular disease compared…
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‘Simple 7’ CV health components associated with lower diabetes risk only for adults with normal glucose tolerance

Joseph JJ, et al. Diabetologia. 2019;doi:10.1007/s00125-018-4792-y.
Among healthy adults with normal glucose tolerance, adherence to four or more cardiovascular health factors proposed by the American Heart…
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Pregnancy glucose level affects childhood glucose, insulin resistance

Scholtens DM, et al. Diabetes Care, 2019;doi:10.2337/dc18-2021.
Higher levels of maternal glucose in utero are associated with higher levels of glucose and insulin resistance in childhood regardless of BMI and a…
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Uric acid to creatinine ratio predicts metabolic syndrome in women

Kawamoto R, et al. Metab Syndr Relat Disord. 2019;doi:10.1089/met.2018.0055.
In Japanese women, baseline serum uric acid to creatinine ratio was a strong and independent predictor of incident metabolic syndrome over 3 years;…
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End-stage kidney disease risk in diabetes not influenced by elevated HbA1c

Limkunakul C, et al. J Diabetes Complications. 2019;doi:10.1016/j.jdiacomp.2018.12.010.
Higher levels of HbA1c do not increase the composite risk for end-stage kidney disease and death in adults with diabetes, according to findings…
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No association observed between baseline HbA1c, BMI and outcomes with fast-acting insulin aspart

Bowering K, et al. Diabetes Ther. 2018;doi:10.1007/s13300-018-0553-7.
Among adults with type 2 diabetes, neither baseline HbA1c nor baseline BMI significantly influenced treatment differences observed between patients…
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Burosumab safe, effective in children with rare form of rickets

Whyte MP, et al. Lancet Diabetes Endocrinol. 2019;doi:10.1016/s2213-8587(18)30338-3.
Young children with X-linked hypophosphatemia saw significant improvements in rickets and phosphate homeostasis after 63 weeks of biweekly treatment…
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