EXPERT SUMMARIES of the top 30 journals in endocrinology
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Risk for additional autoimmune diseases substantial for women, white adults with type 1 diabetes

Bao YK, et al. J Diabetes. 2018;doi:10.1111/1753-0407.12856.
Among those with type 1 diabetes, white adults and women are at a significantly higher risk for developing additional autoimmune diseases as they age…
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Prenatal androgen exposure associated with male psychosexuality in disorders of sex development

Batista RL, et al. J Clin Endocrinol Metab. 2018;doi:10.1210/jc.2018-01866.
Exposure to prenatal androgens, and not virilization of external genitalia, is associated with many psychosexual outcomes, including self-reported…
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Concomitant polyvascular disease, type 2 diabetes sharply raise ischemic risk

Bonaca MP, et al. Lancet Diabetes Endocrinol. 2018;doi:10.1016/s2213-8587(18)30290-0.
Verma S, et al. Lancet Diabetes Endocrinol. 2018;doi:10.1016/s2213-8587(18)30311-5.
Patients with acute coronary syndrome with polyvascular disease and concomitant type 2 diabetes are at heightened long-term risk for ischemic events…
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Hypoglycemia risks differ by ethnicity among adults prescribed insulin, sulfonylureas

Malawana M, et al. Diabet Med. 2018;doi:10.1111/dme.13828.
Among adults with type 2 diabetes, those of black Caribbean ethnicity prescribed insulin are at increased risk for hypoglycemia as are those of black…
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Obesity linked to earlier death for men, women

Bhaskaran K, et al. Lancet Diabetes Endocrinol. 2018;doi:10.1016/s2213-8587(18)30288-2.
Tobias DK, et al. Lancet Diabetes Endocrinol. 2018;doi:10.1016/s2213-8587(18)30309-7.
A nonsmoking man aged 40 years with obesity can expect to live on average 4.2 years less than a similar man of healthy weight, whereas a nonsmoking…
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Different risk factors predict diabetic retinopathy, nephropathy in type 2 diabetes

Song KH, et al. J Diabetes Investig. 2018;doi:10.1111/jdi.12953.
Progression of diabetic retinopathy is associated with increased HbA1c, whereas risk factors for diabetic nephropathy include HbA1c variability and…
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Subclinical hypothyroidism negatively affects brain volumes, cognitive function

Ittermann T, et al. Thyroid. 2018;doi:10.1089/thy.2017.0561.
High levels of thyrotropin are linked to a decrease in brain volume, and even subclinical hypothyroidism may lead to reduced hippocampal volume…
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Gestational weight gain does not influence offspring bone parameters in obesity

Monjardino MT, et al. J Bone Miner Res. 2018;doi:10.1002/jbmr.3587.
In mothers with overweight or obesity, gestational weight gain was not associated with bone mineralization in offspring at age 7 years; however…
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Anlotinib shows promise for treating medullary thyroid cancer

Sun Y, et al. Thyroid.2018;doi:10.1089/thy.2018.0022.
The novel tyrosine kinase inhibitor anlotinib was shown to provide adequate therapeutic benefits for tumor reduction in adults with locally advanced…
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CDC: Prevalence of diabetes in pregnancy rising in US

Deputy NP, et al. Morb Mortal Wkly Rep. 2018; doi:10.15585/mmwr.mm6743a2.
The prevalence of both gestational diabetes and preexisting diabetes before pregnancy in the United States increased slightly between 2012 and 2016…
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Reduced quality of life, fear of recurrence remain in adults with DTC

Hedman C, et al. Thyroid. 2018;doi:10.1089/thy.2018.0388.
Self-reported health-related quality of life is negatively affected by a diagnosis of differentiated thyroid cancer, or DTC, but outlook does improve…
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Lifestyle behaviors, race influence cardiometabolic risk during menopause transition

Ward E, et al. J Clin Endocrinol Metab. 2018;doi:10.1210/jc.2018-00941.
Consuming a healthy diet and being physically active can lower the risk for developing metabolic syndrome during the menopause transition; however…
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Genetic factors may distinguish form of ‘type 1.5 diabetes’

Cousminer DL, et al. Diabetes Care. 2018;doi:10.2337/dc18-1032.
The strongest genetic risk loci for latent autoimmune diabetes in adults are shared with type 1 diabetes; however, established type 2 diabetes…
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Hyperglycemia hospitalization exacerbates mortality risk in adults with diabetes, dementia

Liu CL, et al. J Diabetes Complications.2018;doi:10.1016/j.jdiacomp.2018.10.014.
Adults diagnosed with dementia who also have type 2 diabetes are at increased risk for hospitalization due to severe hyperglycemia and shorter life…
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4 key variables may best predict PCOS

Deshmukh H, et al. Clin Endocrinol. 2018;doi:10.1111/cen.13879.
A new risk prediction score for polycystic ovary syndrome suggests that four clinical variables may best predict the condition in women, including…
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