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Takotsubo cardiomyopathy occurs in some patients with pheochromocytoma, paraganglioma

August 4, 2017

Takotsubo-like catecholamine cardiomyopathy occurred in nearly 3% of patients with secreting pheochromocytoma and paraganglioma, researchers in Canada reported.

“Pheochromocytoma and paraganglioma (PPGL) may occur sporadically or as part of hereditary syndrome,” Nadia Gagnon, MD, of the division of endocrinology at Centre Hospitalier de l’Universite de Montreal, and colleagues wrote. “At least one-third of all patients with PPGL have disease-causing germline mutations. In the presence of acute Takotsubo cardiomyopathy, there is a paucity of literature available on the completion of biochemical testing to exclude PPGL, but clearly not all cases are screened.”

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