71st Scientific Sessions
SAN DIEGO Age-related hearing loss occurs more frequently among
patients with diabetes compared with people who do not have diabetes. Although
the mechanism to explain this association remains unclear, results of a new
meta-analysis demonstrate a 2.28-fold increase in the association between
diabetes and hearing impairment.
Hirohito Sone, MD, PhD, professor in the department of endocrinology and metabolism, University of Tsukuba Mito medical center, and colleagues
analyzed data from 13 observational studies of 8,797 hearing impairment cases
and 11,264 non-hearing impairment cases. Nine studies included
population-based participants and four included hospital-based participants.
Studies were identified using MEDLINE and EMBASE databases and were
cross-sectional in design, with an outcome of non-idiopathic progressive
hearing impairment not due to noise or heredity. In all
studies, hearing impairment was defined by cut-off values of pure-tone
thresholds measured at a frequency range that included 2,000 Hz, and data on
hearing impairment and non-hearing impairment in the presence of diabetes were
The odds ratio for hearing impairment in diabetes was 2.88 (95% CI,
1.82-2.86). Additionally, in studies of patients with a mean age younger than
60 years, and those with patients in hospital settings, the researchers found a
positive association between hearing impairment and diabetes (OR=2.04 and
OR=3.68). In all studies, the risk for hearing impairment associated with
diabetes was consistently positive.
We found that this relationship was strongly established by this
study, and hearing loss should be considered an established complication of
diabetes, Sone told Endocrine Today at the Presidents Poster
reception. The hearing test should be determined in all diabetic patients
whenever possible. by Stacey L. Fisher
For more information:
- Horikawa C. 0426-PP. Presented at: American Diabetes
Associations 71st Scientific Sessions; June 24-28, 2011; San Diego,
Disclosures: Dr. Sone reports no relevant financial disclosures.