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Basal insulin plus GLP-1 improves HbA1c in type 2 diabetes

August 21, 2017

Adults with type 2 diabetes inadequately treated with basal insulin who add a GLP-1receptor agonist experience greater changes in HbA1c compared with those who add a rapid-acting insulin or increase their basal insulin dose, according to a study.

Philip Levin, MD, of Model Clinical Research in Towson, Maryland, and colleagues evaluated data from the MarketScan database on 8,034 adults with type 2 diabetes not adequately controlled using basal insulin alone who underwent treatment intensification within 6 months of showing poor glycemic control to determine the clinical and economic outcomes associated with the addition of a GLP-1 receptor agonist or rapid-acting insulin or an increase in basal insulin dose. Outcomes were evaluated 12 months after treatment intensification.

In the Journals

Continuous glucose monitoring may benefit patients with type 2 diabetes

August 21, 2017
Adults with type 2 diabetes who had more than one insulin injection daily and continuous glucose monitoring for 24 hours experienced improved glycemic control…
In the Journals Plus

Grip strength not tied to incident type 2 diabetes

August 21, 2017
Grip strength during a 10-year period does not appear to be associated with the risk for incident type 2 diabetes in adults, according to findings published in Diabetes
In the Journals Plus

Adverse psychosocial profile common in women with diabetes, acute coronary syndrome

August 21, 2017
Women with diabetes and incident acute coronary syndrome are more likely to report depression and anxiety compared with women without diabetes and men with diabetes…
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Practical Lipidology®: Volume 3, Number 2

This activity is supported by an educational grant from Amgen

The reduction of low-density lipoprotein-cholesterol (LDL-C) is recognized as the primary strategy for decreasing…
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Meeting News

VIDEO: Diabetes language matters

August 5, 2017
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Resource Centers

Diabetic Retinopathy: Preferred Practice Patterns in Screening and Management

This activity is supported by an educational grant from Regeneron.

Diabetic retinopathy (DR) is a major cause of blindness among American adults aged 40 years and older. The prevalence…
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