Cardiometabolic Disorders

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Age at menarche associated with hypertension, obesity risk

November 20, 2017

Chinese women who experience late menarche are more likely to develop hypertension in adulthood but less likely to develop obesity vs. women who reach menarche at age 14 to 15 years, according to findings reported in Menopause.

Gang Liu, MD, of the department of cardiology at the First Affiliated Hospital of Chongqing Medical University, China, and colleagues analyzed data from 7,119 women (mean age, 45 years) who participated in a cross-sectional study launched in October 2012 and completed in December 2014 in eight rural districts in Chongqing. Participants underwent physical exams and completed a questionnaire about lifestyle habits, age at menarche and previous medical history. Obesity was defined as BMI of at least 28 kg/m²; abdominal obesity was defined as waist circumference at least 80 cm in women. Hypertension was defined as previously diagnosed with or without treatment, or average systolic BP at least 140 mm Hg and/or diastolic BP of least 90 mm Hg. Researchers stratified women by age at menarche (age 11 years or younger, 12 to 13 years, 14 to 15 years, 16 to 17 years and at least 18 years) and birth cohort (born before 1950, born between 1951-1979 and born after 1980). Researchers used binary logistic regression analysis to assess the association between age at menarche, obesity and hypertension, with ORs computed across menarcheal ages.

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