A recent comprehensive review published in The Journal of Clinical Endocrinology & Metabolism identifies metformin, sulfonylureas, DPP-IV inhibitors and GLP-1 receptor agonists as preferred therapies for type 2 diabetes in adults who also have osteoporosis.

Stavroula A. Paschou, MD, PhD, of the National and Kapodistrian University of Athens, Greece, and colleagues systematically reviewed past human studies and guidelines to develop recommendations for choosing medications to use when a patient has diabetes and osteoporosis.