In alopecia areata, combination tofacitinib and oral minoxidil therapy may be superior to tofacitinib alone, according to researchers from Yale University School of Medicine, in the top Healio Dermatology story from last week.
Other popular news included platelet-rich plasma (PRP) for ulcer healing and the characteristics of skin microbiota in patients with rosacea. Read on for the top 5 stories.
Tofacitinib plus oral minoxidil promotes hair regrowth in severe alopecia
“Janus kinase inhibitors are emerging as an important therapy for severe alopecia areata and the possibility of increasing efficacy without increasing Janus kinase inhibitor dosage (and immunomodulation and cost of treatment) would be welcome,” Carlos G. Wambier, MD, PhD, and colleagues wrote. Read more.
Platelet-rich plasma may facilitate ulcer healing
Platelet-rich plasma, or PRP, appears to yield healing in ulcers as it changes the matrix metalloproteinase and cytokine expression shortly after topical application. Read more.
Skin microbiota in rosacea differs from healthy skin
Individuals with rosacea showed changes from that of healthy skin, indicating that more research is warranted to understand the pathophysiology of the disease, according to findings from a case-control study published in American Journal of Clinical Dermatology. Read more.
Adapalene/benzoyl peroxide gel reduces atrophic acne scars, lesions up to 48 weeks
After 24 weeks of treatment with adapalene/benzoyl peroxide gel, atrophic acne scarring and lesions were reduced, and results were maintained after 48 weeks of treatment in adult patients. Read more.
Topical solution from Aclaris clears warts by day 29 in phase 3 study
Aclaris Therapeutics announced positive results from a phase 3 clinical trial of A-101 45% topical solution, an investigational new drug for the treatment of common warts. Read more.