Neuromyelitis Optica Spectrum Disorder: Optimizing Clinical Decision-Making in a Rapidly Evolving Therapeutic Landscape

Overview

Provider Statement

This continuing education activity is provided by 

Support Statement

This activity is supported by an educational grant from Horizon Therapeutics USA, Inc.

Activity Description

Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disease of the central nervous system that mainly manifests through recurrent attacks of optic neuritis and longitudinally extensive transverse myelitis. Although early detection is critical for improved outcomes, misdiagnosis is common during the early stages of disease. The application of newer diagnostic criteria and methods may facilitate a differential diagnosis. Until recently, treatment options have been limited, but the emergence of monoclonal antibody therapies has led to a notable shift in therapeutic paradigms. In this educational activity, faculty emphasize the importance of early detection and review clinical evidence that can be used to guide clinical decision-making. An expert panel of clinicians will present hot topics in NMOSD management and discuss clinical cases that address important diagnostic and treatment challenges.

Target Audience

The intended audience for this activity is neurologists, neuro-ophthalmologists, ophthalmologists, physician associates, nurse practitioners, and other healthcare professionals involved in the management of patients with NMOSD.

Learning Objectives

Upon successful completion of this activity, participants should be better able to:

• Apply diagnostic tools for early detection of NMOSD.
• Implement clinical evidence and registry data for currently approved therapies for NMOSD.

Activity Chair

Benjamin M. Greenberg, MD, MHS, FANA, FAAN, CRND
Distinguished Teaching Professor
Vice Chair for Clinical and Translational Research
Department of Neurology
Director, Perot Foundation Neurosciences Translational Research Center
O’Donnell Brain Institute
University of Texas Southwestern
Dallas, TX

Faculty

Patricia K. Coyle, MD, FAAN, FANA
Professor and Vice Chair of Academic Affairs
Department of Neurology
Director
Stony Brook MS Comprehensive Care Center
Stony Brook Renaissance School of Medicine
Stony Brook, NY

Megan R. Weigel, DNP, ARNP-c, MSCN
Advanced Registered Nurse Practitioner
Baptist Neurology
Baptist Health
Jacksonville Beach, FL

Planners/Reviewers

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
Linda A. Giarraputo, BS, PA-C

Accreditation

In support of improving patient care, Vindico Medical Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Credit Designation

Vindico Medical Education designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Vindico Medical Education has been authorized by the American Academy of Physician Associates (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 0.75 AAPA Category 1 CME credits. Approval is valid until March 30, 2024. PAs should only claim credit commensurate with the extent of their participation.

This activity is approved for 0.75 contact hour(s) of continuing education (which includes 0.5 hour(s) of pharmacology) by the American Association of Nurse Practitioners®. Activity ID# 23036006. This activity was planned in accordance with AANP Accreditation Standards and Policies.

This enduring material is approved for 1 year from the date of original release, March 31, 2023, to March 30, 2024.

How to Participate in This Activity and Obtain CE Credit

To participate in this CE activity, you must read the objectives, answer the polling and pretest questions, view the content, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 3 of the 4 posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ certificate, AAPA Category 1 CME credit certificate, or Contact Hour certificate.

Disclosures

Vindico Medical Education adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a continuing education activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Relationship information is accurate at the time of content development.

Activity Chair and Faculty report the following relevant financial relationship(s)

Patricia K. Coyle, MD, FAAN, FANA
Consultant: Horizon, Viela Bio
Independent Research Contractor: Genentech/Roche

Benjamin M. Greenberg, MD, MHS, FANA, FAAN, CRND
Consultant: Alexion, Genentech/Roche, Horizon

Megan R. Weigel, DNP, ARNP-c, MSCN
Consultant: Horizon
Speaker Contracted by Ineligible Company: Horizon

Planners/Reviewers reports the following relevant financial relationship(s)

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
No relevant financial relationships to disclose.

Linda A. Giarraputo, BS, PA-C
No relevant financial relationships to disclose.

Vindico Medical Education staff report the following relevant financial relationship(s)

No relevant financial relationships to disclose.

Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Unlabeled and Investigational Usage

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of US Food and Drug Administration (FDA)–approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2023 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

CME Questions?

Contact us at cme@vindicoCME.com