Among pediatric patients who undergo cardiac surgery, early postoperative acetaminophen exposure may be associated with a lower rate of acute kidney injury, according a study published in JAMA Pediatrics. Further analysis of these findings could establish acetaminophen as a preventative agent for acute kidney injury.
“In our study, we found that children who underwent cardiac surgery were less likely to have postoperative [acute kidney injury] AKI if they received acetaminophen in the first 48 hours after surgery, even after we took measure to adjust for how sick the patients were, the length of cardiac surgery and other risk factors for acute kidney injury,” Sara L. Van Driest, MD, PhD, lead author of the study from Vanderbilt University School of Medicine, told Healio Nephrology. “The more acetaminophen they received, the lower the risk for AKI.”
This activity is supported by an educational grant from Novartis Pharmaceuticals Corporation.
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