USMLE Step 1 - Question 41

A 56 year old female has a history of hypertension, diabetes mellitus type II, elevated low density lipoprotein levels, and smokes tobacco. Which of the above is the most significant risk factor for the development of atherosclerotic heart disease?

A. Hypertension

B. Diabetes mellitus type II

C. Elevated low density lipoprotein

D. Tobacco use