Summary: Patients with unstable angina or non-ST elevation myocardial infarction were randomized to early invasive strategy (including percutaneous coronary intervention or PCI) or initial conservative therapy. The primary endpoint of death, non-fatal MI or refractory angina was significantly reduced at 4 months, however not at 1 year in high risk patients undergoing the early invasive strategy. There was a decrease in death and MI at 5 years in the high risk patients undergoing the early invasive strategy.
Lancet. 2002 Sep 7;360(9335):743-51.
Lancet. 2005 Sep 10-16;366(9489):914-20.
Eponym: Randomized Intervention Trial of Unstable Angina