Summary: Evaluated perindopril versus placebo in patients with and without hypertension and stroke or transient ischemic attacks. The primary endpoint of stroke was reduced by perindopril in patients with OR without hypertension. When indapamide was added there was a further benefit to reduce blood pressure and stroke.

Original Publication:

Lancet. 2001 Sep 29;358(9287):1033-41.

Eponym: The Perindopril pROtection aGainst REcurrent Stroke Study