Acronym: Prospective Global Registry for the Study of Chronic Total Occlusion Intervention

Purpose: Researchers determined the frequency of chronic total occlusion percutaneous coronary intervention procedures, the strategies used and the procedural outcomes

Format: Prospective, cohort, registry

Number of Participants: 3,055

Centers: 20

Summary: Overall technical success was 87% and procedural success was 85%. The rate of in-hospital major complications was 3%, including myocardial infarction in 1.1%, death in 0.9%, pericardial tamponade in 0.9%, stroke in 0.3% and emergency coronary artery bypass graft surgery in 0.2%. Complications were less frequent in technically successful procedures (2.2% vs. 7.9%; P < .0001). Antegrade wire escalation was used in 75% as the initial approach, especially for patients with lower-complex chronic total occlusions, while antegrade dissection re-entry and the retrograde approach were used for more complex lesions.

Original Publication:

Tajti P, et al. JACC Cardiovasc Interv. 2018;doi:10.1016/j.jcin.2018.02.036.

Link to Cardiology Today Article: