The Global Anticoagulant Registry in the FieldAtrial Fibrillation trial assessed antithrombotic therapy patterns in patients newly diagnosed with nonvalvular AF at least one other stroke risk factor.

Design: Prospective, registry

Patients: 39,620

Centers: Multicenter

Countries: 35

Results: The percentage of patients prescribed anticoagulant therapy increased from 57.4% in 2010-11 to 71.1% in 2014-15. Use of non-vitamin K oral anticoagulants with or without an antiplatelet rose from 4.2% in 2010-2011 to 37% in 2014-15. Use of vitamin K antagonists with or without an antiplatelet declined from 53.2% in 2010-11 to 34% in 2014-15. Use of antiplatelet monotherapy declined from 30.2% in 2010-11 to 16.6% in 2014-15. Predictors of non-vitamin K oral anticoagulant prescription included male sex, age 65 or older, Asian ethnicity, dementia, use of nonsteroidal anti-inflammatory drugs and current smoking.

Original Publications:
Camm AJ, et al. Heart. 2017;doi:10.1136/heartjnl-2016-309832.

Healio/Cardiology News Coverage:
More patients with AF receive guideline-recommended anticoagulant therapy