FAME 2 Trial

Summary: Evaluated using fractional flow reserve (FFR) guided percutaneous coronary intervention (PCI) versus best medical therapy. The primary endpoint of composite all-cause mortality, nonfatal MI or unplanned hospitalization leading to urgent PCI was significantly reduced in the FFR guided PCI group.

Original Publication:

N Engl J Med. 2012 Aug 27.

Eponym: Fractional Flow Reserve Versus Angiography for Multivessel Evaluation 2 Trail