Acronym: American College of Cardiology (ACC) Foundation/STS Collaboration on the Comparative Effectiveness of Revascularization Strategies Trial
Purpose: Evaluated percutaneous coronary intervention (PCI) versus coronary artery bypass grafting (CABG)
Format: Nonrandomized, observational
Treatment Group 1: PCI
Treatment Group 2: CABG
Number of Patients: 1,943,653
- Single-vessel disease
- Left main coronary artery disease
- Cardiogenic shock
- Myocardial infarction
- Insertion of an intraaortic balloon pump before either procedure
- CABG or valve surgery or PCI within 180 days
Primary Endpoint: all-cause mortality
Follow-up: mean 2.72
The ASCERT trial found that CABG reduced all-cause mortality at 4 years compared to PCI. At 1 year there was no difference in all-cause mortality.
Weintraub WS, et al. N Engl J Med. 2012;doi: 10.1056/NEJMoa1110717.