Summary: Evaluated patients on statin therapy randomized to extended-release niacin versus ezetimibe. The primary endpoint of carotid intima media thickness was reduced with niacin, however increased with ezetimibe. Patients on ezetimibe also had more cardiovascular events.

Original Publication:

N Engl J Med 2009; 361:2113-2122

Eponym: ARterial Biology for the Investigation of Treatment Effects of Reducing Cholesterol 6 - HDL And LDL Treatment Study