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Reduction in apoB particles may play key role in benefit from LDL lowering

Reduction in apoB particles may play key role in benefit from LDL lowering
August 31, 2017

Drop in risk for CV events corresponded more closely with reduction in apolipoprotein B levels than with reduction in LDL levels, according to a Mendelian randomization study published in JAMA.

“The clinical benefit of lowering LDL levels may therefore depend on the corresponding reduction in apoB-containing lipoprotein particles,” Brian A. Ference, MD, MPhil, MSc, from the division of cardiovascular medicine at Wayne State University School of Medicine, Detroit, and colleagues wrote.

In the JournalsPerspective

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2 decades of molecular cardiology and genetics

Cardiology Today, August 2017
Robert Roberts, MD, FRCPC, MACC, FRSC, LLD (Hon.)
Editor’s Note: Cardiology Today is celebrating its 20th anniversary in 2017. We are reaching out to experts in cardiology for their take on changes in CV medicine
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The Patient with Heart Failure

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Over 5 million people in the United States (US) over the age of 20 years have heart failure (HF) and the prevalence of…
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