Chandler and Grant's Glaucoma, Fifth Edition

Malik Y Kahook, MD ; Joel S Schuman, MD

  • $198.95
  • ISBN 10 1-55642-954-1
  • ISBN 13 978-1-55642-954-5
  • 752 pp Hard Cover
  • Pub. Date: 2013
  • Order# 69545

Chandler and Grant’s Glaucoma, now in its Fifth Edition, represents a timely update to one of the field’s seminal texts on the medical practice and surgical management of glaucoma.

Edited by Drs. Malik Y. Kahook and Joel S. Schuman and with contributions from David L. Epstein and over 60 contributors, Chandler and Grant’s Glaucoma, Fifth Edition brings together the experience of world-class glaucoma experts who belong to a long line of surgeons trained by using the teachings of the original authors of this classic work.

Meticulous updating from the previous edition maintains the well-established historical teachings of Drs. Paul A. Chandler and W. Morton Grant and defines this new Fifth Edition as the most relevant and invaluable reference on the topic of glaucoma.

Exploring subject areas from the mechanisms behind clinical observation to the details on treating the individual patient in the office, Chandler and Grant’s Glaucoma, Fifth Edition brings together the experience of world-class glaucoma experts trained from the original teachings of this book.

New topics and features in the Fifth Edition:
• Advances in imaging of the optic nerve and retina
• Updates on medical therapy of glaucoma
• New approaches for minimally invasive glaucoma surgery
• Over 400 images and tables

Chandler and Grant’s Glaucoma has been an invaluable reference for the medical and surgical management of glaucoma for generations of ophthalmologists. This updated Fifth Edition builds on the teachings of previous editions, while expanding on new knowledge, making the Fifth Edition as relevant in the 21st century as when the first lectures were presented by Drs. Chandler and Grant.

A Doody's Core Title Selection!

Dedication
Acknowledgments 
About the Editors 
Contributing Authors 
Preface 
Introduction

Section I The Basics 
Chapter 1 Introduction 
Joel S. Schuman, MD, FACS and David L. Epstein, MD, MMM
Chapter 2 Anatomy
Malik Y. Kahook, MD and E. Michael Van Buskirk, M D
Peripapillary Atrophy: Joel S. Schuman, MD, FACS and Malik Y. Kahook, MD 
Chapter 3 Practical Aqueous Humor Dynamics 
Joel S. Schuman, MD, FACS; Malik Y. Kahook, MD; and David L. Epstein, MD, MMM
An Interesting Question: David L. Epstein, MD, MMM 
Testing of New Glaucoma Drugs: David L. Epstein, MD, MMM 
Chapter 4 The Patient’s History: Symptoms of Glaucoma 
Joel S. Schuman, MD, FACS and David L. Epstein, MD, MMM
Steroid-Induced Elevation of Intraocular Pressure: David L. Epstein, MD, MMM 
Chapter 5 Examination of the Eye 
Ian P. Conner, MD, PhD; Joel S. Schuman, MD, FACS; Malik Y. Kahook, MD; and
David L. Epstein, MD, MMM
The Rule of 5%: David L. Epstein, MD, MMM 
Chapter 6 Tonometry and Tonography 
Jeremy B. Wingard, MD and Joel S. Schuman, MD, FACS
Chapter 7 The Angle of the Anterior Chamber 
Joel S. Schuman, MD, FACS; Deval Joshi, MD; and Lisa S. Gamell, MD
Gonioscopy During Operation: Joel S. Schuman, MD, FACS 
Chapter 8 Examination of the Optic Nerve 
Ian P. Conner, MD, PhD; Joel S. Schuman, MD, FACS; and David L. Epstein, MD, MMM
Clinical Assessment of the Nerve Fiber Layer: Joel S. Schuman, MD, FACS
Chapter 9 Imaging of the Optic Nerve Head and Nerve Fiber Layer 
Lindsey S. Folio, MS, MBA; Gadi Wollstein, MD; and Joel S. Schuman, MD, FACS
Chapter 10 Imaging Devices for Angle Assessment 
Mina B. Pantcheva, MD and Malik Y. Kahook, MD
Chapter 11 Visual Fields and Their Relationship to the Optic Nerve 
Joshua D. Stein, MD, MS and R. Rand Allingham, MD

Section II Medications Used in Glaucoma Therapy 
Chapter 12 Adrenergic Agents: Blockers and Agonists 
Pratap Challa, MD, MS and David L. Epstein, MD, MMM
Evaluating Clinical Trials: Pratap Challa, MD, MS and David L. Epstein, MD, MMM 
Timolol and Albino Rabbits: Pratap Challa, MD, MS and David L. Epstein, MD, MMM 
Laboratory Glaucoma Models: Pratap Challa, MD, MS and David L. Epstein, MD, MMM 
Statistical and Clinical Significance: Pratap Challa, MD, MS and David L. Epstein, MD, MMM 
Mechanisms of Epinephrine-Induced Cystoid Macular Edema: Pratap Challa, MD, MS and
David L. Epstein, MD, MMM
Chapter 13 The Miotics 
Pratap Challa, MD, MS and David L. Epstein, MD, MMM
Acetylcholinesterase: David L. Epstein, MD, MMM 
Drug Therapy Compliance: David L. Epstein, MD, MMM 
Limited Duration of Activity of Phospholine Iodide: David L. Epstein, MD, MMM 
Chapter 14 Carbonic Anhydrase Inhibitors: Systemic Use 
Pratap Challa, MD, MS and David L. Epstein, MD, MMM
Chapter 15 Topical Carbonic Anhydrase Inhibitors 
Pratap Challa, MD, MS and Joel S. Schuman, MD, FACS
Chapter 16 Prostaglandin Analogs 
Angela V. Turalba, MD and Douglas J. Rhee, MD
Chapter 17 Management of Highly Elevated Intraocular Pressure 
Joshua D. Stein, MD, MS; R. Rand Allingham, MD; and Pratap Challa, MD, MS

Section III Common Open-Angle Glaucomas 
Chapter 18 Primary Open-Angle Glaucoma 
Kimberly V. Miller, MD; Joel S. Schuman, MD, FACS; and David L. Epstein, MD, MMM
Primary Open-Angle Glaucoma and Myopia: David L. Epstein, MD, MMM 
Common Mistakes in Glaucoma Management: David L. Epstein, MD, MMM 
Trabecular Glaucoma Versus Optic Nerve Glaucoma: David L. Epstein, MD, MMM 
Tonography: David L. Epstein, MD, MMM 
Chapter 19 Low-Tension Glaucoma 
Ian P. Conner, MD, PhD; Kimberly V. Miller, MD; Joel S. Schuman, MD, FACS; and
David L. Epstein, MD, MMM
Low-Tension Glaucoma and the General Ophthalmologist: David L. Epstein, MD, MMM 
Ocular Effects of Calcium-Channel Blockers: Past Promise: Peter A. Netland, MD, PhD 
Chapter 20 Pseudoexfoliation Syndrome and Open-Angle Glaucoma 
Pratap Challa, MD, MS and David L. Epstein, MD, MMM
Tonography in Pseudoexfoliation: Pratap Challa, MD, MS and David L. Epstein, MD, MMM 
Chapter 21 Pigment Dispersion and Pigmentary Glaucoma 
Ian P. Conner, MD, PhD; Kimberly V. Miller, MD; Joel S. Schuman, MD, FACS; and
David L. Epstein, MD, MMM
Tonography: David L. Epstein, MD, MMM 

Section IV Angle-Closure Glaucoma 
Chapter 22 Principles of Primary Angle-Closure Glaucoma 
George Ulrich, MD, FACS and David L. Epstein, MD, MMM
Iris Retraction Syndrome: David L. Epstein, MD, MMM 
Pseudo-Unilateral Angle Closure: David L. Epstein, MD, MMM 
Chapter 23 Acute Angle-Closure Glaucoma: Diagnosis and Treatment 
George Ulrich, MD, FACS; Joel S. Schuman, MD, FACS; David L. Epstein, MD, MMM; and
Ian P. Conner, MD, PhD
Anterior Chamber Deepening With Mechanical Breaking of Peripheral Anterior Synechiae With an
Iris Spatula (Goniosynechialysis): David L. Epstein, MD, MMM 
Chapter 24 Subacute (and Chronic) Angle-Closure Glaucoma 
George Ulrich, MD, FACS and David L. Epstein, MD, MMM
Chapter 25 Angle-Closure Glaucoma: Evaluation and Treatment After Iridotomy 
Mina B. Pantcheva, MD; Malik Y. Kahook, MD; and David L. Epstein, MD, MMM
Chapter 26 Plateau Iris
Joel S. Schuman, MD, FACS; Malik Y. Kahook, MD; and David L. Epstein, MD, MMM
Chapter 27 The Use of Special Tests in Narrow-Angled Eyes 
Joel S. Schuman, MD, FACS and David L. Epstein, MD, MMM
Goniolens Characteristics: R. Rand Allingham, MD 

Section V Secondary Angle-Closure Glaucomas 
Chapter 28 Principles of Secondary Angle-Closure Glaucomas 
David L. Epstein, MD, MMM
Chapter 29 The Malignant Glaucoma Syndromes 
Ian P. Conner, MD, PhD; Joel S. Schuman, MD, FACS; and David L. Epstein, MD, MMM
The History of Mydriatic-Cycloplegic Therapy: David L. Epstein, MD, MMM
The Chandler Operation: Ian P. Conner, MD, PhD; Joel S. Schuman, MD, FACS; and
David L. Epstein, MD, MMM

Chapter 30 Nanophthalmos: Diagnosis and Treatment 
Zvia Burgansky-Eliash, MD and Richard J. Simmons, MD
Chapter 31 Neovascular Glaucoma 
Jeffrey R. SooHoo, MD; David K. Dueker, MD; and Malik Y. Kahook, MD
Chapter 32 Iridocorneal Endothelial Syndromes 
Sarwat Salim, MD, FACS and M. Bruce Shields, MD
Chapter 33 Glaucoma After Vitreoretinal Procedures 
Ron A. Adelman, MD, MPH, MBA, FACS and Martin Wand, MD
Intraocular Gas and Altitude: Martin Wand, MD and Ron A. Adelman, MD, MPH, MBA, FACS
Chapter 34 Angle-Closure Glaucoma Due to Multiple Cysts of the Iris and Ciliary Body 
Ian P. Conner, MD, PhD; Joel S. Schuman, MD, FACS; and David L. Epstein, MD, MMM
Chapter 35 Angle-Closure Glaucoma Secondary to Occlusion of the Central Retinal Vein 
Malik Y. Kahook, MD and David L. Epstein, MD, MMM
Chapter 36 Angle-Closure Glaucoma Secondary to Acute Myopia 
Malik Y. Kahook, MD and David L. Epstein, MD, MMM
Acute Bilateral Transitory Myopia Associated With Open-Angle Glaucoma: Joel S. Schuman, MD, FACS 
Chapter 37 Glaucoma After Penetrating Keratoplasty 
Mina B. Pantcheva, MD; Joel S. Schuman, MD, FACS; Malik Y. Kahook, MD; and
David L. Epstein, MD, MMM

Section VI Combined Mechanisms 
Chapter 38 Combined Open-Angle and Angle-Closure Glaucoma 
Joel S. Schuman, MD, FACS and David L. Epstein, MD, MMM
Chapter 39 Glaucoma in the Pseudophakic and Aphakic Eye 
Ian P. Conner, MD, PhD; Joel S. Schuman, MD, FACS; and David L. Epstein, MD, MMM
Glaucoma Surgery in Pseudophakia and Aphakia: A Historical Perspective: R. Rand Allingham, MD 
Chapter 40 Characteristically Unilateral Glaucomas: Differential Diagnosis 
Joel S. Schuman, MD, FACS; Malik Y. Kahook, MD; and David L. Epstein, MD, MMM
Chapter 41 Glaucoma Secondary to Intraocular Tumors 
Sumit P. Shah, MD and Jay S. Duker, MD

Section VII Secondary Open-Angle Glaucoma 
Chapter 42 Glaucoma Due to Intraocular Inflammation 
Zvia Burgansky-Eliash, MD; Guy Aharon Weiss, MD; and R. Rand Allingham, MD
Chapter 43 Glaucoma Due to Trauma 
Carla I. Bourne, MD and Bradford J. Shingleton, MD
Secondary Glaucoma in Black Patients: A Historical Perspective: Morton F. Goldberg, MD 
Iris Retraction Syndrome: Joel S. Schuman, MD, FACS 
Chapter 44 Corticosteroid Glaucoma 
Mina B. Pantcheva, MD
Chapter 45 Hemolytic or Ghost-Cell Glaucoma 
David L. Epstein, MD, MMM
Chapter 46 Glaucoma Associated With Extraocular Venous Congestion (Increased Episcleral Venous Pressure) 
Ian P. Conner, MD, PhD; Joel S. Schuman, MD, FACS; and David L. Epstein, MD, MMM
Aqueous Humor Dynamics: A Trick Question: David L. Epstein, MD, MMM 
Chapter 47 Lens-Induced Glaucoma 
Ian P. Conner, MD, PhD; Joel S. Schuman, MD, FACS; and David L. Epstein, MD, MMM
Understanding Lens-Induced Glaucomas: Ian P. Conner, MD, PhD and David L. Epstein, MD, MMM 
Completely Dislocated Hypermature Cataract and Glaucoma: Ian P. Conner, MD, PhD;
Joel S. Schuman, MD, FACS; and David L. Epstein, MD, MMM 
Chapter 48 Amyloidosis and Open-Angle Glaucoma 
David L. Epstein, MD, MMM
Chapter 49 Glaucoma in the Phakomatoses 
Cynthia Mattox, MD and Priti Batta, MD
Chapter 50 Juvenile Open-Angle Glaucoma 
Janey L. Wiggs, MD, PhD

Section VIII Laser Methods in Glaucoma 
Chapter 51 Glaucoma Laser Surgery 
Jeremy B. Wingard, MD and Joel S. Schuman, MD, FACS
Chapter 52 Laser Trabeculoplasty 
Jeremy B. Wingard, MD and Joel S. Schuman, MD, FACS
Chapter 53 Laser Trabeculoplasty: How Does It Work? 
Daniel Cotlear, MD; Shlomo Melamed, MD; and Modi Goldenfeld, MD
How I Do Laser Trabeculopasty:  Claudia U. Richter, MD
Chapter 54 Post-Laser Elevation of Intraocular Pressure 
Marshall N. Cyrlin, MD
Chapter 55 Laser Peripheral Iridotomy 
Lisa S. Gamell, MD; Timothy Saunders, MD; and Joel S. Schuman, MD, FACS
The Choice of Iridotomy Lens: Joel S. Schuman, MD, FACS 
Technique of Laser Iridotomy: Lisa S. Gamell, MD
Which Laser Should I Use?: Lisa S. Gamell, MD
One Technique for Laser Peripheral Iridotomy: Joel S. Schuman, MD, FACS 
Chapter 56 Cyclodestruction 
Mina B. Pantcheva, MD and Joel S. Schuman, MD, FACS
Chapter 57 Laser Peripheral Iridoplasty 
Lisa S. Gamell, MD and Cristan M. Arena, MD
Practical Considerations for Argon Laser Peripheral Iridoplasty: Lisa S. Gamell, MD 
Personal Technique: Lisa S. Gamell, MD 

Section IX Glaucoma Surgery 
Chapter 58 What to Say to Glaucoma Patients Prior to Filtration Surgery 
Mahmoud A. Khaimi, MD
Chapter 59 Filtering Surgery in the Management of Glaucoma 
Mahmoud A. Khaimi, MD and Marcos Reyes, MD
Antiproliferative Therapy for Filtration Surgery: Mahmoud A. Khaimi, MD; Marcos Reyes, MD; and
David A. Lee, MD, MS, MBA, FACS, FARVO 
Externalized Releasable Sutures in Filtering Surgery: Murray A. Johnstone, MD and Annisa L. Jamil, MD 
How to Handle Mitomycin C: David P. Tingey, BA, MD, FRCSC 
Chapter 60 Postoperative Management Following Filtration Surgery 
Mahmoud A. Khaimi, MD and Marcos Reyes, MD
Performing a Choroidal Tap: R. Rand Allingham, MD
Treatment of Hypotonous Maculopathy: Mahmoud A. Khaimi, MD; Marcos Reyes, MD;
and R. Rand Allingham, MD 
Chapter 61 The Management of Coexisting Cataract and Glaucoma 
Carla I. Bourne, MD; Bradford J. Shingleton, MD; and Joel S. Schuman, MD, FACS
Chapter 62 Aqueous Shunting Procedures 
Sarwat Salim, MD, FACS and Malik Y. Kahook, MD
Chapter 63 Cyclodialysis
David L. Epstein, MD, MMM
Mystery Diagnosis: David L. Epstein, MD, MMM 
Chapter 64 Surgical Peripheral Iridectomy 
David L. Epstein, MD, MMM
Chapter 65 Schlemm’s Canal Surgery for Glaucoma Management 
Steven R. Sarkisian Jr, MD and Marcos Reyes, MD
Chapter 66 Suprachoroidal Approach to Glaucoma Surgery 
Ramesh S. Ayyala, MD, FRCS(E), FRCOphth(Lon); Farhan A. Irshad, MD; and
Iqbal “Ike” K. Ahmed, MD, FRCSC
Chapter 67 Treatment of Occludable Angles and Angle Closure With Cataract Extraction 
Michael A. Alunni, MD and Garry P. Condon, MD

Section X Diagnosis and Treatment of Glaucoma in Children 
Chapter 68 Pediatric Glaucoma 
Richard W. Hertle, MD, FAAO, FACS, FAAP
Chapter 69 Unusual Pediatric Glaucomas 
Vicki M. Chen, MD and David S. Walton, MD

Section XI Special Considerations 
Chapter 70 The Role of the Cornea in Managing Glaucoma 
Leon W. Herndon Jr, MD
Chapter 71 Twenty-Four-Hour Intraocular Pressure Monitoring in Glaucoma 
Brian J. Song, MD and Lama A. Al-Aswad, MD
Chapter 72 The Role of Ocular Perfusion Pressure in the Pathogenesis of Glaucoma 
Yvonne Ou, MD and Sanjay Asrani, MD
Topical Medications and Ocular Perfusion Pressure: Yvonne Ou, MD and Sanjay Asrani, MD 
Chapter 73 Neuroprotection in Glaucoma 
Yvonne Ou, MD and Stuart J. McKinnon, MD, PhD
Chapter 74 Adherence to Glaucoma Medical Therapy 
Lisa S. Gamell, MD and Gretta Fridman, MD
What Do We Actually Do to Ensure Adherence?: Lisa S. Gamell, MD 
Chapter 75 Epidemiology of Glaucoma 
Michael B. Horsley, MD and M. Roy Wilson, MD, MS

Financial Disclosures 
Index 

“One of the more innovative aspects of the book is the use of case presentations at the end of many chapters from the authors’ own patient vignettes, demonstrating how they applied the information they present in the book to actual practice…Already one of my personal favorites, this is my go-to reference when teaching residents and medical students. Since glaucoma knowledge has advanced tremendously since the 1997 edition, this updated edition is much appreciated.” 

            -Christopher B. Chambers, MD, Doody’s Review Service

Malik Y. Kahook, MD is Professor of Ophthalmology and Director of Clinical and Translational Research in the Department of Ophthalmology at the University of Colorado. He also directs the glaucoma service and glaucoma fellowship. Dr. Kahook specializes in the medical and surgical treatment of glaucoma and cataracts. He is active within the ophthalmology community, including memberships in the American Academy of Ophthalmology, American Glaucoma Society, American Society of Refractive and Cataract Surgeons, and the Association for Research in Vision and Ophthalmology. Dr. Kahook has authored more than 200 peer-reviewed manuscripts, abstracts, and book chapters, and is editor of 4 textbooks, including Essentials of Glaucoma Surgery (SLACK Incorporated). He is on the editorial board of the American Journal of Ophthalmology and International Glaucoma Review, among others. He was awarded an American Glaucoma Society Clinician-Scientist Fellowship Award for 2007, as well as the American Glaucoma Society Compliance Grant for 2006, and was named New Inventor of the Year for the University of Colorado in 2009 and Inventor of the Year for 2010. Dr. Kahook received the American Academy of Ophthalmology Achievement Award in 2011. He has filed for more than 12 patents, several of which have been licensed by companies for development and commercialization. He currently serves as a consultant to the US Food and Drug Administration’s Ophthalmic Device Division. 
 Dr. Kahook completed his residency training at the University of Colorado, Rocky Mountain Lions Eye Institute in Denver, Colorado, where he was named Chief Resident. He then went on to complete his fellowship in glaucoma from the University of Pittsburgh Medical Center in Pittsburgh, Pennsylvania.

Joel S. Schuman, MD, FACS is the Eye and Ear Foundation Professor and Chairman of Ophthalmology, the Eye and Ear Institute, University of Pittsburgh School of Medicine and Director of the University of Pittsburgh Medical Center (UPMC) Eye Center. He is also Professor of Bioengineering at the Swanson School of Engineering, University of Pittsburgh, and a Founder of the Louis J. Fox Center for Vision Restoration of UPMC and the University of Pittsburgh. He is a member of the McGowan Institute for Regenerative Medicine and the Center for the Neural Basis of Cognition, Carnegie Mellon University and University of Pittsburgh. Dr. Schuman is a native of Roslyn, New York; he graduated from Columbia University (BA, 1980) and Mt. Sinai School of Medicine (MD, 1984). Following his internship at New York’s Beth Israel Medical Center (1985), he completed residency training at Medical College of Virginia (1988) and glaucoma fellowship at Massachusetts Eye & Ear Infirmary (clinical 1989; research 1990), where he was a Heed Fellow. After just over a year on the Harvard faculty, he moved to the New England Medical Center, Tufts University, to co-found the New England Eye Center in 1991, where he was Residency Director and Glaucoma and Cataract Service Chief. In 1998, he became Professor of Ophthalmology, and Vice Chair in 2001.

Dr. Schuman and his colleagues were the first to identify a molecular marker for human glaucoma, as published in Nature Medicine in 2001. He has been continuously funded by the National Eye Institute as a principal investigator since 1995, is principal investigator of a National Institutes of Health (NIH) grant to study novel glaucoma diagnostics, and is co-investigator of NIH grants for research into novel optical diagnostics and short pulse laser surgery and for advanced imaging in glaucoma. He is an inventor of optical coherence tomography (OCT), used world-wide for ocular diagnostics. Dr. Schuman has published more than 250 peer-reviewed scientific journal articles, has authored or edited 8 books, and has contributed more than 50 book chapters.

In 2002, Dr. Schuman received the Alcon Research Institute Award, as well as the New York Academy of Medicine’s Lewis Rudin Glaucoma Prize. In 2003, he received the Senior Achievement Award from the American Academy of Ophthalmology. In 2004, he was elected into the American Society for Clinical Investigation. In 2006, he received the Association for Research in Vision and Ophthalmology (ARVO) Translational Research Award. He was elected to the American Ophthalmological Society in 2008. He received a 2006-2009 American Medical Association Physician’s Recognition Award with Commendation. In 2010, he became a silver Fellow of ARVO. In 2011, Dr. Schuman was the Clinician-Scientist Lecturer of the American Glaucoma Society. In 2012, he received the Carnegie Science Center’s Award in Life Sciences and was a co-recipient of the Champalimaud Award.

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