Ulcerative Colitis: The Complete Guide to Medical Management

Gary R. Lichtenstein, MD, FACP, FACG, AGAF

Chapter 12: Assessment of Disease Activity in Ulcerative Colitis (continued)

Anthony L. Rose, MD; Thomas A. Judge, MD

ASSESSMENT OF DISEASE ACTIVITY IN ULCERATIVE COLITIS An objective evaluation of disease activity is essential for treating patients with inflammatory bowel disease (IBD). Throughout the years, many indices of disease activity have been proposed for both Crohn’s disease (CD) and ulcerative colitis (UC). Perhaps the most recognized and widely used is the Crohn’s disease activity index (CDAI) introduced by Best et al in 19761 and modified by Harvey and Bradshaw in 1980.2 The most widely recognized disease activity index for patients with UC was introduced by Truelove and Witts in…