Probiotics: A Clinical Guide

Martin H. Floch, MD; Adam S. Kim, MD

Chapter 19: Probiotics And Pouchitis (continued)

Mario Guslandi, MD, FACG

Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the surgical treatment of choice for patients with refractory UC, dysplasia complicating UC, or familial adenomatous polyposis (FAP).1,2 The most common long-term complication after IPAA for UC—but not FAP—is inflammation of the ileal reservoir, called pouchitis,2-4 occurring in 24% to 60% of cases.2,4-6 About 60% of patients undergo 1 or more recurrences and 5% to 32% of them develop chronic pouchitis, which in turn may require pouch excision in 10% of the cases.2,