Curbside Consultation in IBD: 49 Clinical Questions, Second Edition

David T Rubin, MD; Sonia Friedman, MD; Francis A Farraye, MD MSc

Question 30: What Is The Optimal Management Of Ulcerative Proctosigmoiditis? (continued)

Douglas C. Wolf, MD

Ulcerative proctosigmoiditis is a form of ulcerative colitis (UC) characterized by inflammation of the distal colon, up to a length of approximately 25 cm from the anus. It involves a greater extent of the colon than ulcerative proctitis, which involves the rectum alone, up to 15 cm. Ulcerative proctosigmoiditis is not as extensive as left-sided colitis, which involves approximately 40 to 50 cm of the colon up to the splenic flexure, or pancolitis, which involves the colon from the rectum to beyond the splenic flexure. UC disease distribution is localized to rectum and sigmoid…