Ulcerative Colitis: The Complete Guide to Medical Management

Gary R. Lichtenstein, MD, FACP, FACG, AGAF

Chapter 35: Prebiotics and Probiotics of Ulcerative Colitis (continued)

Robert M. Penner, BSc, MD, FRCP(C), MSc; Karen L. Madsen, PhD; Massimo Campieri, MD; Richard N. Fedorak, MD, FRCPC

PREBIOTICS AND PROBIOTICS IN ULCERATIVE COLITIS Bacteria have long been known to act as pathogenic agents, sometimes as mediators of enteric infections. This knowledge has motivated the medical study of bacteria, but research has only recently begun to focus on the complex symbiotic interaction between the mammalian host and native, endogenous, intestinal microflora. With the understanding that inflammatory bowel disease (IBD) represents a derangement of the human relationship with our procaryotic guests has come the opportunity to explore therapies that create or restore a healthy colonic…